[PDF][PDF] THE ROLE OF ANIMAL MODELS IN PHARMACOKINETIC-PHARMACODYNAMIC MODELLING FOR THE EVALUATION OF CONJUGATED ANTIBODIES

Z Rustemi, I Gjorgoski, E Janevik-Ivanovska - KNOWLEDGE-International …, 2021 - ikm.mk
The purpose of this analysis is to explain the usage of animal model in pharmacokinetic-
pharmacodynamic (PK/PD) behavior of conjugated antibodies intended for radioactive …

MICROORGANISMS AS OBJECTS FOR EXAMINATION GENOTOXICITY WITH THE USE OF AMES TEST

A Coneva, N Velickova, V Taleski - KNOWLEDGE-International Journal, 2022 - ikm.mk
Ames test or analysis of reversible mutation of Salmonella typhimurium is a test for
identification or detection (screening) of substances that cause genotoxicity or have a …

[PDF][PDF] Thesis submitted to the University of Strathclyde in fulfilment of the for the degree of Master of Philosophy

R Snell - 2020 - scholar.archive.org
Biotherapeutics are becoming of greater importance within the pharmaceutical industry, with
companies expanding their portfolios into this area and an increasing number of …

[PDF][PDF] RATE OF SKIN ADVANCED GLYCATION END-PRODUCTS ACCUMULATION MEASURED BY BIOPSIES AND SKIN AUTOFLUORESCENCE IN DIABETIC …

S Arsov - KNOWLEDGE-International Journal, 2021 - ikm.mk
The objectives of the study was to measure the rate of accumulation of different advanced
glycation end-products in the skin of diabetic hemodialysis patients over a period of one …

[PDF][PDF] THE RELIABILITY OF THE ANALYTICAL METHODS FOR DETERMINATION OF CONJUGATED ANTIBODIES AFTER FINAL PREPARATION IN SERUM …

Z Rustemi, DM Wanjeh, P Apostolova, AA Marie… - KNOWLEDGE …, 2021 - ikm.mk
Understanding the pharmacokinetics and biodistribution of conjugated antibodies is one of
the critical steps in enabling their successful development and use. Their complex structure …