Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

Radical-involved transition metal (TM) catalysis has greatly enabled new reactivities in
recent decades. Copper-catalyzed radical relay offers enormous potential in C (sp3)–H …

C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

Radical–radical couplings are mostly nearly diffusion‐controlled processes. Therefore, the
selective cross‐coupling of two different radicals is challenging and not a synthetically …

Conspectus The direct transformation of C–H bonds into diverse functional groups
represents one of the most atom-and step-economical strategies for organic synthesis and …

Copper-catalyzed radical-relay reactions provide a versatile strategy for selective C–H
functionalization; however, reactions with peroxide-based oxidants often require excess C …

Site-selective radical reactions of benzylic C–H bonds are now highly effective methods for
C (sp3–H) functionalization and cross-coupling. The existing methods, however, are often …

A method for direct cross coupling between unactivated C (sp3)–H bonds and
chloroformates has been accomplished via nickel and photoredox catalysis. A diverse range …

A visible‐light‐driven, copper‐catalyzed three‐component radical cross‐coupling of oxime
esters, styrenes, and boronic acids has been developed. Key steps of this protocol involve …

Site selectivity represents a key challenge for non-directed C–H functionalization, even
when the C–H bond is intrinsically reactive. Here, we report a copper-catalyzed method for …