Cannabinoids and the expanded endocannabinoid system in neurological disorders

L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Phytocannabinoids: origins and biosynthesis

T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

CDKL5 deficiency disorder: clinical features, diagnosis, and management

H Leonard, J Downs, TA Benke, L Swanson… - The Lancet …, 2022 - thelancet.com
CDKL5 deficiency disorder (CDD) was first identified as a cause of human disease in 2004.
Although initially considered a variant of Rett syndrome, CDD is now recognised as an …

Use of cannabidiol in the treatment of epilepsy: efficacy and security in clinical trials

S Silvestro, S Mammana, E Cavalli, P Bramanti… - Molecules, 2019 - mdpi.com
Cannabidiol (CBD) is one of the cannabinoids with non-psychotropic action, extracted from
Cannabis sativa. CBD is a terpenophenol and it has received a great scientific interest …

Epilepsy and cannabidiol: a guide to treatment

A Arzimanoglou, U Brandl, JH Cross, A Gil-Nagel… - Epileptic …, 2020 - shs.cairn.info
Epilepsy and cannabidiol: a guide to treatment | Cairn.info Cairn.info, Matières à réflexion
Cairn.info, Matières à réflexion Aucune suggestion trouvée Compte personnel Adresse email …

Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure …

S McGrath, LR Bartner, S Rao… - Journal of the …, 2019 - Am Vet Med Assoc
OBJECTIVE To assess the effect of oral cannabidiol (CBD) administration in addition to
conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy …

Cyclin-dependent kinase-like 5 deficiency disorder: clinical review

HE Olson, ST Demarest, EM Pestana-Knight… - Pediatric …, 2019 - Elsevier
Abstract Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a
developmental encephalopathy caused by pathogenic variants in the gene CDKL5. This …

[HTML][HTML] Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access …

LC Laux, EM Bebin, D Checketts, M Chez, R Flamini… - Epilepsy research, 2019 - Elsevier
Background Since 2014, patients with severe treatment-resistant epilepsies (TREs) have
been receiving add-on cannabidiol (CBD) in an ongoing, expanded access program (EAP) …

Pharmacological and therapeutic properties of cannabidiol for epilepsy

V Franco, E Perucca - Drugs, 2019 - Springer
Cannabidiol (CBD) is a major active component of the Cannabis plant, which, unlike
tetrahydrocannabinol (THC), is devoid of euphoria-inducing properties. During the last 10 …