Pyridine compounds with antimicrobial and antiviral activities

M Marinescu, CV Popa - International journal of molecular sciences, 2022 - mdpi.com
In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …

1, 2, 4-Oxadiazole as a potential scaffold in agrochemistry: a review

L Zhong, C Wu, M Li, J Wu, Y Chen, Z Ju… - Organic & Biomolecular …, 2023 - pubs.rsc.org
N, O-containing heterocycles have been incorporated into various approved pesticides and
pesticide candidates. The persistent challenge in contemporary crop protection lies in the …

Design, synthesis, biological evaluation and molecular docking of new uracil analogs-1, 2, 4-oxadiazole hybrids as potential anticancer agents

AE El Mansouri, A Oubella, M Maatallah… - Bioorganic & Medicinal …, 2020 - Elsevier
A new series of uracil analogues-1, 2, 4-oxadiazole hybrid derivatives were synthesized by
a new, simple, and efficient method using for the first time HAP-SO 3 H as an heterogenous …

Synthesis and anticancer evaluation of new lipophilic 1, 2, 4 and 1, 3, 4-oxadiazoles

W Caneschi, KB Enes, CC de Mendonça… - European journal of …, 2019 - Elsevier
Abstract A series of1, 2, 4-and 1, 3, 4-oxadiazole derivatives were synthesized and
evaluated for their anticancer activity. Halogenated 1, 2, 4-oxadiazoles were obtained from …

Design, synthesis, and study of the insecticidal activity of novel steroidal 1, 3, 4-Oxadiazoles

S Ma, W Jiang, Q Li, T Li, W Wu, H Bai… - Journal of Agricultural …, 2021 - ACS Publications
A series of novel steroidal derivatives with a substituted 1, 3, 4-oxadiazole structure was
designed and synthesized, and the target compounds were evaluated for their insecticidal …

Synthesis and biological evaluation of novel 7-hydroxy-4-phenylchromen-2-one–linked to triazole moieties as potent cytotoxic agents

CF Liu, QK Shen, JJ Li, YS Tian… - Journal of Enzyme …, 2017 - Taylor & Francis
A new series of novel 7-hydroxy-4-phenylchromen-2-one (1a)–linked 1, 2, 4-triazoles were
synthesised using a click chemistry approach. All derivatives were subjected to 3-(4, 5 …

Current Advancement in the Oxadiazole-Based Scaffolds as Anticancer Agents

G Kapoor, R Bhutani, DP Pathak… - Polycyclic Aromatic …, 2022 - Taylor & Francis
Heterocyclic nucleus is vital in medicinal chemistry and has allured significant attention in
chemotherapeutic domain. Oxadiazole, a five-membered nitrogen–oxygen-containing …

Synthesis, biological activity and toxicity to zebrafish of benzamides substituted with pyrazole-linked 1, 2, 4-oxadiazole

Y Shao, M Tu, S Yang, Y Wang, B Sun, J Shi, C Tan… - RSC …, 2022 - pubs.rsc.org
To find pesticidal lead compounds with high activity, a series of novel benzamides
substituted with pyrazole-linked 1, 2, 4-oxadiazole was designed and synthesized by using …

Synthesis and electrochemical and antioxidant properties of chalcogenocyanate oxadiazole and 5-heteroarylchalcogenomethyl-1 H-tetrazole derivatives

JG Leal, AC Sauer, JCP Mayer, ST Stefanello… - New Journal of …, 2017 - pubs.rsc.org
This article presents the chalcogenocyanate oxadiazoles 7 and 8 and their derivatives 5-
heteroarylchalcogenomethyl-1H-tetrazoles 9 and 10, which were synthesized in high yields …

Novel 3′-Substituted-1′,2′,4′-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and …

AV Markov, AV Sen'kova, II Popadyuk… - International Journal of …, 2020 - mdpi.com
A series of novel 18βH-glycyrrhetinic acid (GA) derivatives containing 3′-
(alkyl/phenyl/pyridin (-2 ″,-3 ″, and-4 ″)-yl)-1′, 2′, 4′-oxadiazole moieties at the C-30 …