The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

The interstitium describes the fluid, proteins, solutes, and the extracellular matrix (ECM) that
comprise the cellular microenvironment in tissues. Its alterations are fundamental to …

Microvascular fluid exchange (flow J v) underlies plasma/interstitial fluid (ISF) balance and
oedematous swelling. The traditional form of Starling's principle has to be modified in light of …

This review aims at presenting state-of-the-art knowledge on the composition and functions
of the endothelial glycocalyx. The endothelial glycocalyx is a network of membrane-bound …

Over the past decade, since it was first observed in vivo, there has been an explosion in
interest in the thin (∼ 500 nm), gel-like endothelial glycocalyx layer (EGL) that coats the …

Replacement of assumed preoperative deficits, in addition to generous substitution of an
unsubstantiated increased insensible perspiration and third space loss, plays an important …

Purpose In 2007 the two senior authors wrote a review on the structure and function of the
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …

This review addresses classical questions concerning microvascular permeabiltiy in the light
of recent experimental work on intact microvascular beds, single perfused microvessels, and …

Myocardial tissue edema attributable to increased microvascular fluid loss contributes to
cardiac dysfunction after myocardial ischemia, cardiopulmonary bypass, hypertension, and …

Endothelial cells are covered with a polysaccharide rich layer more than 400 nm thick,
mechanical properties of which limit access of circulating plasma components to endothelial …