TAFRO syndrome is associated with anti-SSA/Ro60 antibodies, in contrast to idiopathic castleman disease

M Shirakashi, Y Nishida, R Nakashima, M Fujimoto… - Scientific Reports, 2024 - nature.com
TAFRO syndrome is an acute systemic inflammatory disease characterized by
thrombocytopenia, anasarca, fever, reticulin fibrosis/renal dysfunction, and organomegaly …

Association of combined anti‐Ro52/TRIM21 and anti‐Ro60/SSA antibodies with increased Sjögren disease severity through interferon pathway activation

E Bettacchioli, A Saraux, A Tison… - Arthritis & …, 2024 - Wiley Online Library
Objective The biologic diagnosis of primary Sjögren disease (SjD) mainly relies on anti‐
Ro60/SSA antibodies, whereas the significance of anti‐Ro52/TRIM21 antibodies currently …

[HTML][HTML] Ro60—Roles in RNA Processing, Inflammation, and Rheumatic Autoimmune Diseases

RS Mahla, EL Jones, LB Dustin - International Journal of Molecular …, 2024 - mdpi.com
The Ro60/SSA2 autoantigen is an RNA-binding protein and a core component of
nucleocytoplasmic ribonucleoprotein (RNP) complexes. Ro60 is essential in RNA …

Isolated anti-Ro52 identifies a severe subset of Sjögren's syndrome patients

AYS Lee, T Putty, MW Lin, S Swaminathan… - Frontiers in …, 2023 - frontiersin.org
Introduction Serum autoantibodies targeting the SSA/Ro proteins are a key component of
the classification criteria for the diagnosis of Sjögren's syndrome (SS). Most patients' serum …

UHFUS: a valuable tool in evaluating exocrine gland abnormalities in Sjögren's disease

G Fulvio, R Izzetti, G Aringhieri, V Donati, F Ferro… - Diagnostics, 2023 - mdpi.com
Sjögren's Disease (SjD) is a chronic autoimmune disorder that affects the salivary and
lacrimal glands, leading to xerostomia and xerophthalmia. Ultrasonography of Major …

Impact of IgG Fc Glycosylation on Disease Dynamics in Patients With Primary Sjögren Disease

H Achten, L Meuris, L Deroo, M Jarlborg… - Arthritis & …, 2025 - Wiley Online Library
Objective Glycans attached to the Fc region of IgG antibodies influence their pro‐or anti‐
inflammatory effector function. We aimed to explore the interrelation of the Fc glycosylation …

Seronegative patients with primary Sjögren's syndrome and non-pSS sicca test positive for anti-SSA/Ro52 and-Ro60 in saliva

S Kamounah, F Wei, JK Park, YW Song, D Chia… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Objectives Testing for anti-SSA/Ro antibodies in serum is essential in the diagnostic work-up
for primary Sjögren's syndrome (pSS). In this study, we aimed to validate our previous assay …

Clinical Profile of Patients with Primary Sjögren's Syndrome with Non-Identified Antinuclear Autoantibodies

D Parisis, J Sarrand, X Cabrol, C Delporte, MS Soyfoo - Diagnostics, 2024 - mdpi.com
Objectives—The aim of the present study was to characterize the clinical phenotype of
patients with primary Sjögren's syndrome (pSS) with non-identified antinuclear antibodies …

POS0902 ANTI-SSA RO52 AND ANTI-RO60 AUTOANTIBODIES: ASSOCIATION WITH CLINICAL PHENOTYPES

C Mazeda, N Oliveira, C Abreu, V Fraga… - Annals of the Rheumatic …, 2023 - Elsevier
Background Anti-SSA autoantibodies can be differentiated according to their antigenic target
proteins as anti-Ro60 (60 kDa) or anti-Ro52 (52 kDa). Anti-SSA (Ro60) are clearly …

[HTML][HTML] Accuracy of Labial Salivary Gland Biopsy in Suspected Cases of Sjogren's Syndrome

AI AlMannai, K Alaradi, SAI Almahari - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Introduction: Sjögren's syndrome (SS) is a chronic autoimmune disorder primarily
characterized by dysfunction of the exocrine glands, leading to dryness of the eyes and …