The IL-1 family cytokines and receptors in autoimmune diseases
P Migliorini, P Italiani, F Pratesi, I Puxeddu… - Autoimmunity …, 2020 - Elsevier
The role of the cytokines and receptors of the IL-1 family in inflammation is well known.
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …
[HTML][HTML] IL-33/IL-31 axis in immune-mediated and allergic diseases
Several allergic and immunologic diseases including asthma, food allergy (FA), chronic
spontaneous urticaria (CSU), atopic dermatitis (AD), systemic lupus erythematosus (SLE) …
spontaneous urticaria (CSU), atopic dermatitis (AD), systemic lupus erythematosus (SLE) …
Role of IL-33 in inflammation and disease
AM Miller - Journal of inflammation, 2011 - Springer
Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss
Decidualization renders the endometrium transiently receptive to an implanting blastocyst
although the underlying mechanisms remain incompletely understood. Here we show that …
although the underlying mechanisms remain incompletely understood. Here we show that …
The roles of IL-1 family cytokines in the pathogenesis of systemic sclerosis
D Xu, R Mu, X Wei - Frontiers in immunology, 2019 - frontiersin.org
The IL-1 family consists of 11 cytokines, 7 ligands with agonist activity (IL-1α, IL-1β, IL-18, IL-
33, IL-36α, IL-36β, IL-36γ) and four members with antagonistic activities [IL-1 receptor …
33, IL-36α, IL-36β, IL-36γ) and four members with antagonistic activities [IL-1 receptor …
Soluble ST2 in heart failure
B Dieplinger, T Mueller - Clinica Chimica Acta, 2015 - Elsevier
In addition to routine clinical laboratory tests (including natriuretic peptides and cardiac
troponins), other biomarkers are gaining attention for their utility in heart failure (HF) …
troponins), other biomarkers are gaining attention for their utility in heart failure (HF) …
Interleukin-33 Ameliorates Experimental Colitis through Promoting Th2/Foxp3+ Regulatory T-Cell Responses in Mice
L Duan, J Chen, H Zhang, H Yang, P Zhu, A **ong… - Molecular …, 2012 - Springer
Crohn's disease (CD) is characterized by the activation of Th1 and Th17 cells and deficiency
of regulatory T cells (Tregs), leading to intestine tissue injury and destruction. As a novel …
of regulatory T cells (Tregs), leading to intestine tissue injury and destruction. As a novel …
Therapeutic potential of targeting interleukin‐1 family cytokines in chronic inflammatory skin diseases
L Calabrese, Z Fiocco, TK Satoh… - British Journal of …, 2022 - academic.oup.com
Summary The interleukin (IL)‐1 family of cytokines is a central regulator of a myriad of
immunological responses. It comprises several cytokines, including those belonging to the …
immunological responses. It comprises several cytokines, including those belonging to the …
Production and functions of IL-33 in the central nervous system
S Yasuoka, J Kawanokuchi, B Parajuli, S **, Y Doi… - Brain research, 2011 - Elsevier
Interleukin-33 (IL-33) is a novel multifunctional IL-1 family cytokine. IL-33 signals via a
heterodimer composed of IL-1 receptor-related protein ST2 and IL-1 receptor accessory …
heterodimer composed of IL-1 receptor-related protein ST2 and IL-1 receptor accessory …
Immunotherapy strategy for systemic autoimmune diseases: Betting on CAR-T cells and antibodies
Systemic autoimmune diseases (SAIDs), such as systemic lupus erythematosus (SLE),
systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated …
systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated …