Polymeric hydrogels are fascinating platforms as 3D scaffolds for tissue repair and delivery
systems of therapeutic molecules and cells. Among others, methacrylated gelatin (GelMA) …

During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

As the gap between donors and patients in need of an organ transplant continues to widen,
research in regenerative medicine seeks to provide alternative strategies for treatment. One …

Abstract Chitin (CT), the well-known natural biopolymer and chitosan (CS)(bio-based or
“artificial polymer”) are non-toxic, biodegradable and biocompatible in nature. The …

The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …

Nanocomposites have emerged in the last two decades as an efficient strategy to upgrade
the structural and functional properties of synthetic polymers. Aliphatic polyesters as …

Biomimetic nanofibrous scaffolds mimicking important features of the native extracellular
matrix provide a promising strategy to restore functions or achieve favorable responses for …

Promoting bone regeneration and repairing defects are urgent and critical challenges in
orthopedic clinical practice. Research on bone substitute biomaterials is essential for …

Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …

Growth factors are endogenous signaling molecules that regulate cellular responses
required for wound healing processes such as migration, proliferation, and differentiation …