After three decades of developments, single particle tracking (SPT) has become a powerful
tool to interrogate dynamics in a range of materials including live cells and novel catalytic …

We summarize experimental observations of fluorescence intermittency of single
semiconductor nanocrystals and single molecules. We review the main models proposed …

Single-particle tracking experiments have been used widely to study the heterogeneity of a
sample. Segments with dissimilar diffusive behaviors are associated with different …

The interest in membrane heterogeneity started with two biological questions: how is the
plasma membrane organized on a microscopic scale and what is the influence of this …

While critical to biological processes, molecular diffusion is difficult to quantify, and spatial
map** of local diffusivity is even more challenging. Here we report a machine-learning …

The optical signals of single molecules provide information about structure and dynamics of
their nanoscale environment, free from space and time averaging. These new data are …

Optical microscopy has proven to be one of the most powerful tools in biology, in part
because it allows direct, noninvasive visualization of dynamic processes inside live cells. It …

Supported lipid bilayers (SLBs) have been studied extensively as simple but powerful
models for cellular membranes. Yet, potential differences in the dynamics of the two leaflets …

We describe how a single-particle tracking experiment should be designed in order for its
recorded trajectories to contain the most information about a tracked particle's diffusion …

We propose a Bayesian method to extract the diffusivity of biomolecules evolving freely or
inside membrane microdomains. This approach assumes a model of motion for the particle …