Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for
patients with tumors. They preferentially target and kill tumor cells, leaving healthy cells …

Growing evidence suggests that aberrant epigenetic regulation of gene function is strongly
related to the genesis of cancer. Unlike genetic mutations, the ability to reprogram the …

Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …

Cancer has long been viewed as a disease of normal development gone awry. Cancer stem-
like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as …

MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …

In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …

The discovery of therapeutic miRNAs is one of the most exciting challenges for
pharmaceutical companies. Since the first miRNA was discovered in 1993, our knowledge of …

MicroRNA (miRNA; miR) is a functionally small non-coding RNA and can negatively
regulate gene expression by directly binding to the target gene. Some miRNAs are closely …

To protect tissues and the organism from disease, potentially harmful cells are removed
through programmed cell death processes, including apoptosis and necroptosis. These …