Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …

Over the past two decades, evidence has accumulated that neurogenesis can occur in both
the juvenile and adult mammalian hypothalamus. Levels of hypothalamic neurogenesis can …

Cell proliferation and neuroinflammation in the adult hypothalamus may contribute to the
pathogenesis of obesity. We tested whether the intertwining of these two processes plays a …

Diet-induced obesity leads to devastating and common chronic diseases, fueling ongoing
interest in determining new mechanisms underlying both obesity and its consequences. It is …

Abstract Background Interleukin-6 (IL6) produced in the context of exercise acts in the
hypothalamus reducing obesity-associated inflammation and restoring the control of food …

There is a resurgent interest in tanycytes, a radial glial-like cell population occupying the
floor and ventro-lateral walls of the third ventricle (3V). Tanycytes reside in close proximity to …

Adult neurogenesis, the process of creating new neurons, involves the coordinated division,
migration, and differentiation of neural stem cells. This process is restricted to neurogenic …

A complex neural network regulates body weight and energy balance, and dysfunction in
the communication between the gut and this neural network is associated with metabolic …