New vaccine technologies to combat outbreak situations

S Rauch, E Jasny, KE Schmidt, B Petsch - Frontiers in immunology, 2018 - frontiersin.org
Ever since the development of the first vaccine more than 200 years ago, vaccinations have
greatly decreased the burden of infectious diseases worldwide, famously leading to the …

Phlebotomine sandflies and the spreading of leishmaniases and other diseases of public health concern

M Maroli, MD Feliciangeli, L Bichaud… - Medical and …, 2013 - Wiley Online Library
Phlebotomine sandflies transmit pathogens that affect humans and animals worldwide. We
review the roles of phlebotomines in the spreading of leishmaniases, sandfly fever, summer …

Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence

PM D'Aoust, E Mercier, D Montpetit, JJ Jia, I Alexandrov… - Water research, 2021 - Elsevier
In the absence of an effective vaccine to prevent COVID-19 it is important to be able to track
community infections to inform public health interventions aimed at reducing the spread and …

Phase 1 trials of rVSV Ebola vaccine in Africa and Europe

ST Agnandji, A Huttner, ME Zinser… - … England Journal of …, 2016 - Mass Medical Soc
Background The replication-competent recombinant vesicular stomatitis virus (rVSV)–based
vaccine expressing a Zaire ebolavirus (ZEBOV) glycoprotein was selected for rapid safety …

Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

DF Stojdl, B Lichty, S Knowles, R Marius, H Atkins… - Nature medicine, 2000 - nature.com
Interferons are circulating factors that bind to cell surface receptors, activating a signaling
cascade, ultimately leading to both an antiviral response and an induction of growth …

[HTML][HTML] Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus

S Shelly, N Lukinova, S Bambina, A Berman, S Cherry - Immunity, 2009 - cell.com
Intrinsic innate immune mechanisms are the first line of defense against pathogens and exist
to control infection autonomously in infected cells. Here, we showed that autophagy, an …

Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses

M Garbutt, R Liebscher, V Wahl-Jensen… - Journal of …, 2004 - Am Soc Microbiol
Replication-competent recombinant vesicular stomatitis viruses (rVSVs) expressing the type
I transmembrane glycoproteins and selected soluble glycoproteins of several viral …

The host type I interferon response to viral and bacterial infections

AK Perry, G Chen, D Zheng, H Tang, G Cheng - Cell research, 2005 - nature.com
Type I interferons (IFN) are well studied cytokines with anti-viral and immune-modulating
functions. Type I IFNs are produced following viral infections, but until recently, the …

Isatin derivatives as broad-spectrum antiviral agents: the current landscape

T Elsaman, MS Mohamed, EM Eltayib… - Medicinal Chemistry …, 2022 - Springer
In recent decades, several viruses have resulted in large outbreaks with serious health,
economic and social consequences. The current unprecedented outbreak of the new …

N95 mask decontamination using standard hospital sterilization technologies

A Kumar, SB Kasloff, A Leung, T Cutts, JE Strong… - MedRxiv, 2020 - medrxiv.org
The response to the COVID-19 epidemic is generating severe shortages of personal
protective equipment around the world. In particular, the supply of N95 respirator masks has …