Combined chemotherapy is a treatment method based on the simultaneous use of two or
more therapeutic agents; it is frequently necessary to produce a more effective treatment for …

Melatonin is a serotonin-derived pineal gland hormone with many biological functions like
regulating the sleep-wake cycle, circadian rhythm, menstrual cycle, aging, immunity, and …

There are several pathologies, syndromes, and physiological processes in which autophagy
is involved. This process of self‐digestion that cells trigger as a survival mechanism is …

Melatonin has the ability to intervene in the initiation, progression and metastasis of some
experimental cancers. A large variety of potential mechanisms have been advanced to …

Aim: Cancer constitutes the second leading cause of death worldwide, with conventional
therapies limited by significant side effects. Melatonin (MEL), a natural compound with …

Melatonin is a ubiquitous indole amine that plays a fundamental role in the regulation of the
biological rhythm. Disrupted circadian rhythm alters the expression of clock genes and …

This study investigated the effects of different temperatures on structural characterization
and antitumor activity of polysaccharides from Astragalus membranaceus. APS4 and APS90 …

Melatonin (Mel) serves as an important signalling molecule in various aspects of stress
tolerance in plants. However, the function of Mel in pesticide metabolism remains unknown …

There is considerable evidence that melatonin may be of use in the prevention and
treatment of cancer. This manuscript will review some of the human, animal and cellular …

Within the last few decades, melatonin has increasingly emerged in clinical oncology as a
naturally occurring bioactive molecule with substantial anticancer properties and a …