Azithromycin in COVID-19 patients: pharmacological mechanism, clinical evidence and prescribing guidelines
The global COVID-19 pandemic has led to a race to find medications that can improve the
prognosis of the disease. Azithromycin, in association with hydroxychloroquine or …
prognosis of the disease. Azithromycin, in association with hydroxychloroquine or …
Association of cardiovascular disease with coronavirus disease 2019 (COVID-19) severity: a meta-analysis
Observational studies have reported an association between underlying cardiovascular
diseases (CVD) and worse prognosis in COVID-19 patients, but this still remains unclear …
diseases (CVD) and worse prognosis in COVID-19 patients, but this still remains unclear …
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
W Tang, Z Cao, M Han, Z Wang, J Chen, W Sun, Y Wu… - bmj, 2020 - bmj.com
Objective To assess the efficacy and safety of hydroxychloroquine plus standard of care
compared with standard of care alone in adults with coronavirus disease 2019 (covid-19) …
compared with standard of care alone in adults with coronavirus disease 2019 (covid-19) …
BTS guidelines for the management of community acquired pneumonia in adults: update 2009
WS Lim, SV Baudouin, RC George, AT Hill… - Thorax, 2009 - thorax.bmj.com
SYNOPSIS OF RECOMMENDATIONS A summary of the initial management of patients
admitted to hospital with suspected community acquired pneumonia (CAP) is presented in …
admitted to hospital with suspected community acquired pneumonia (CAP) is presented in …
Azithromycin and the risk of cardiovascular death
WA Ray, KT Murray, K Hall, PG Arbogast… - New England Journal …, 2012 - Mass Medical Soc
Background Although several macrolide antibiotics are proarrhythmic and associated with
an increased risk of sudden cardiac death, azithromycin is thought to have minimal …
an increased risk of sudden cardiac death, azithromycin is thought to have minimal …
COVID-19: therapeutics and their toxicities
SARS-CoV-2 is a novel coronavirus that emerged in 2019 and is causing the COVID-19
pandemic. There is no current standard of care. Clinicians need to be mindful of the toxicity …
pandemic. There is no current standard of care. Clinicians need to be mindful of the toxicity …
Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases
P Zarogoulidis, N Papanas, I Kioumis… - European journal of …, 2012 - Springer
Background Macrolides have long been recognised to exert immunomodulary and anti-
inflammatory actions. They are able to suppress the “cytokine storm” of inflammation and to …
inflammatory actions. They are able to suppress the “cytokine storm” of inflammation and to …
Use of azithromycin and death from cardiovascular causes
Background Azithromycin use is associated with an increased risk of death from
cardiovascular causes among patients at high baseline risk. Whether azithromycin confers a …
cardiovascular causes among patients at high baseline risk. Whether azithromycin confers a …
Cardiotoxicity of antimalarial drugs
NJ White - The Lancet infectious diseases, 2007 - thelancet.com
There are consistent differences in cardiovascular state between acute illness in malaria
and recovery that prolong the electrocardiographic QT interval and have been …
and recovery that prolong the electrocardiographic QT interval and have been …
Triazole antifungal agents in invasive fungal infections: a comparative review
C Lass-Flörl - Drugs, 2011 - Springer
Invasive fungal disease continues to be a problem associated with significant morbidity and
high mortality in immunocompromised and, to a lesser extent, immunocompetent …
high mortality in immunocompromised and, to a lesser extent, immunocompetent …