Macrophages are essential for the maintenance of intestinal homeostasis, yet appear to be
drivers of inflammation in the context of inflammatory bowel disease (IBD). How these …

The gastrointestinal tract has the important task of absorbing nutrients, a complex process
that requires an intact barrier allowing the passage of nutrients but that simultaneously …

Macrophages respond to microbial ligands and various noxious cues by initiating an
inflammatory response aimed at eliminating the original pathogenic insult. Transition of …

Macrophages, which are functional plasticity cells, have the ability to phagocytize and digest
foreign substances and acquire pro-(M1-like) or anti-inflammatory (M2-like) phenotypes …

Circulating monocytes can infiltrate mucosal or inflamed tissues where they differentiate into
either macrophages or dendritic cells. This paradigm is supported by numerous studies …

Macrophages originating from the yolk sac or bone marrow play essential roles in tissue
homeostasis and disease. Bone marrow-derived monocytes differentiate into Ly6Chi and …

The gut and liver are recognized to mutually communicate through the biliary tract, portal
vein, and systemic circulation. However, it remains unclear how this gut-liver axis regulates …

Macrophages are typically identified as classically activated (M1) macrophages and
alternatively activated (M2) macrophages, which respectively exhibit pro-and anti …

Objective Colorectal cancer (CRC) is the third most diagnosed cancer, and requires surgical
resection and reconnection, or anastomosis, of the remaining bowel to re-establish intestinal …

Western-style diets have been implicated in triggering inflammatory bowel disease activity.
The aim of this study was to identify the effect of a short-term diet high in sugar on …