Cognitive function is an important component of aging and predicts quality of life, functional
independence, and risk of institutionalization. Advances in our understanding of the role of …

As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

The ability to investigate therapeutic interventions in animal models of neurodegenerative
diseases depends on extensive characterization of the model (s) being used. There are …

Noncommunicable disease now contributes to the World Health Organization top 10 causes
of death in low-, middle-and high-income countries. Particular examples include stroke …

Cholesterol is an indispensable component of the cell membrane and plays vital roles in
critical physiological processes. Brain cholesterol accounts for a large portion of total …

Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Background: Cohort studies have reported that midlife high total serum cholesterol (TC) is
associated with increased risk of Alzheimer's disease (AD) in late-life but findings have been …

The B rain and B ody D onation P rogram (BBDP) at B anner S un H ealth R esearch I
nstitute (http://www. brainandbodydonationprogram. org) started in 1987 with brain‐only …

Alzheimer's disease (AD) is the most common form of dementia and it is characterized by the
deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. However, the …

More than 25 million people in the world today are affected by dementia, most suffering from
Alzheimer's disease. In both developed and develo** nations, Alzheimer's disease has …