Mechanical ventilation is the most used short-term life support technique worldwide and is
applied daily for a diverse spectrum of indications, from scheduled surgical procedures to …

In late 2019, an outbreak of a novel human coronavirus causing respiratory disease was
identified in Wuhan, China. The virus spread rapidly worldwide, reaching pandemic status …

Background Spontaneous-breathing trials can be performed with the use of either pressure-
support ventilation (PSV) or a T-piece. Whether PSV trials may result in a shorter time to …

Importance Daily spontaneous breathing trials (SBTs) are the best approach to determine
whether patients are ready for disconnection from mechanical ventilation, but mode and …

Rationale: Monitoring and controlling respiratory drive and effort may help to minimize lung
and diaphragm injury. Airway occlusion pressure (P0. 1) is a noninvasive measure of …

Some patients with coronavirus disease (COVID-19) present with severe acute respiratory
syndrome, which causes multiple organ dysfunction, besides dysfunction of the respiratory …

Abstract Treatment of respiratory failure has improved dramatically since the polio epidemic
in the 1950s with the use of invasive techniques for respiratory support: mechanical …

Rationale: Diaphragm dysfunction is frequently observed in critically ill patients with difficult
weaning from mechanical ventilation. Objectives: To evaluate the effects of temporary …

Background Clinicians use several measures to ascertain whether individual patients will
tolerate liberation from mechanical ventilation, including the rapid shallow breathing index …

OBJECTIVES: In mechanically ventilated patients, deep sedation is often assumed to induce
“respirolysis,” that is, lyse spontaneous respiratory effort, whereas light sedation is often …