TRPM7, a divalent cation-selective channel with kinase domains, has been widely reported
to potentially affect cancers. In this study, we conducted multiple bioinformatic analyses …

Purpose Glioblastoma (GBM) is the most common type of adult brain tumor with extremely
poor survival. Cystathionine-gamma lyase (CTH) is one of the main Hydrogen Sulfide (H 2 …

To date, only some cancer patients can benefit from chemotherapy and targeted therapy.
Drug resistance continues to be a major and challenging problem facing current cancer …

Background: It is essential to develop better biomarkers for diagnosis, prediction, and
treating glioma patients to ensure successful clinical outcomes. The clinical application of …

Aims Previous studies have indicated that IFI30 plays a protective role in human cancers.
However, its potential roles in regulating glioma development are not fully understood …

Cancer cachexia is accompanied by muscle atrophy, sharing multiple common catabolic
pathways with sarcopenia, including mitochondrial dysfunction. This study investigated gene …

Background: Glioblastoma (GBM) is the most aggressive and lethal central nervous system
(CNS) tumor. The treatment strategy is mainly surgery and/or radiation therapy, both …

Chaperone-mediated autophagy (CMA) is a homeostatic process essential for the lysosomal
degradation of a selected subset of the proteome. CMA activity directly depends on the …

Background The murine double minute 2 (MDM2) gene is a crucial factor in the
development and progression of various cancer types. Multiple rigorous scientific studies …

One of the main obstacles to therapeutic success in colorectal cancer (CRC) is the
development of acquired resistance to treatment with drugs such as 5-fluorouracil (5-FU) …