Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993‏ - journals.asm.org
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and esca** the host immune response against it. HIV …

The antiviral activity of antibodies in vitro and in vivo

PWHI Parren, DR Burton - 2001‏ - Elsevier
Publisher Summary This chapter discusses in vitro and in vivo antiviral activities of antibody.
Since experimentation is far easier in vitro, researchers have been sought to develop in vitro …

[كتاب][B] Fields' virology

BN Fields - 2007‏ - books.google.com
Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Identification of a heparin-binding motif on adeno-associated virus type 2 capsids

A Kern, K Schmidt, C Leder, OJ Muller… - Journal of …, 2003‏ - journals.asm.org
Infection of cells with adeno-associated virus (AAV) type 2 (AAV-2) is mediated by binding to
heparan sulfate proteoglycan and can be competed by heparin. Mutational analysis of AAV …

Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

A Pegu, Z Yang, JC Boyington, L Wu, SY Ko… - Science translational …, 2014‏ - science.org
HIV-1 infection depends on effective viral entry mediated by the interaction of its envelope
(Env) glycoprotein with specific cell surface receptors. Protective antiviral antibodies …

Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41.

EO Freed, DJ Myers, R Risser - Proceedings of the National Academy of …, 1990‏ - pnas.org
The human immunodeficiency virus transmembrane glycoprotein gp41 has at its amino
terminus a strongly hydrophobic stretch of 28 amino acids flanked by a highly conserved …

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

NK Banda, J Bernier, DK Kurahara, R Kurrle… - The Journal of …, 1992‏ - rupress.org
During human immunodeficiency virus (HIV) infection there is a profound and selective
decrease in the CD4+ population of T lymphocytes. The mechanism of this depletion is not …

Inhibition of entry of HIV-1 in neural cell lines by antibodies against galactosyl ceramide

JM Harouse, S Bhat, SL Spitalnik, M Laughlin… - Science, 1991‏ - science.org
Although the CD4 molecule is the principal cellular receptor for the human
immunodeficiency virus (HIV), several CD4-negative cell lines are susceptible to infection …

HIV-1 gp120 induces TLR2-and TLR4-mediated innate immune activation in human female genital epithelium

A Nazli, JK Kafka, VH Ferreira, V Anipindi… - The Journal of …, 2013‏ - journals.aai.org
Although women constitute half of all HIV-1–infected people worldwide (UNAIDS World
AIDS Day Report, 2011), the earliest events in the female reproductive tract (FRT) during …

AIDS: an international perspective

P Piot, FA Plummer, FS Mhalu, JL Lamboray, J Chin… - Science, 1988‏ - science.org
The acquired immunodeficiency syndrome (AIDS) and infection with the human
immunodeficiency virus type 1 (HIV-1) constitute a worldwide public health problem …