[HTML][HTML] Atherosclerosis: recent developments

JLM Björkegren, AJ Lusis - Cell, 2022 - cell.com
Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

[HTML][HTML] Metabolic-dysfunction-associated steatotic liver disease—its pathophysiology, association with atherosclerosis and cardiovascular disease, and treatments

H Yanai, H Adachi, M Hakoshima, S Iida… - International journal of …, 2023 - mdpi.com
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a chronic liver disease
that affects more than a quarter of the global population and whose prevalence is increasing …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study

R Quispe, SS Martin, ED Michos, I Lamba… - European heart …, 2021 - academic.oup.com
Aims Emerging evidence suggests that remnant cholesterol (RC) promotes atherosclerotic
cardiovascular disease (ASCVD). We aimed to estimate RC-related risk beyond low-density …

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: a multivariable Mendelian randomisation …

TG Richardson, E Sanderson, TM Palmer… - PLoS …, 2020 - journals.plos.org
Background Circulating lipoprotein lipids cause coronary heart disease (CHD). However,
the precise way in which one or more lipoprotein lipid-related entities account for this …

Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms

K Malekmohammad, EE Bezsonov… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

M Bäck, A Yurdagul Jr, I Tabas, K Öörni… - Nature Reviews …, 2019 - nature.com
Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …

Association of triglyceride-lowering LPL variants and LDL-C–lowering LDLR variants with risk of coronary heart disease

BA Ference, JJP Kastelein, KK Ray, HN Ginsberg… - Jama, 2019 - jamanetwork.com
Importance Triglycerides and cholesterol are both carried in plasma by apolipoprotein B
(ApoB)–containing lipoprotein particles. It is unknown whether lowering plasma triglyceride …

Apolipoprotein B particles and cardiovascular disease: a narrative review

AD Sniderman, G Thanassoulis, T Glavinovic… - JAMA …, 2019 - jamanetwork.com
Importance The conventional model of atherosclerosis presumes that the mass of
cholesterol within very low-density lipoprotein particles, low-density lipoprotein particles …