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[HTML][HTML] Recent progress in drug delivery
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …
desired tissues, organs, cells and subcellular organs for drug release and absorption …
Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials
TAS Aguirre, D Teijeiro-Osorio, M Rosa… - Advanced drug delivery …, 2016 - Elsevier
The development of oral dosage forms that allows absorption of therapeutic peptides to the
systemic circulation is one of the greatest challenges for the pharmaceutical industry …
systemic circulation is one of the greatest challenges for the pharmaceutical industry …
A pH‐triggered self‐unpacking capsule containing zwitterionic hydrogel‐coated MOF nanoparticles for efficient oral exendin‐4 delivery
Y Zhou, Z Chen, D Zhao, D Li, C He… - Advanced …, 2021 - Wiley Online Library
Oral peptide or protein delivery is considered a revolutionary alternative to daily
subcutaneous injection; however, major challenges remain in terms of impediments of the …
subcutaneous injection; however, major challenges remain in terms of impediments of the …
[HTML][HTML] Advances in oral peptide drug nanoparticles for diabetes mellitus treatment
Y Li, W Zhang, R Zhao, X Zhang - Bioactive materials, 2022 - Elsevier
Peptide drugs play an important role in diabetes mellitus treatment. Oral administration of
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
Chitosan: A promising therapeutic agent and effective drug delivery system in managing diabetes mellitus
Chitosan, a promising carbohydrate biopolymer is gaining scientific attention in a wide
range of biomedical applications due to its outstanding chemical and pharmacokinetic …
range of biomedical applications due to its outstanding chemical and pharmacokinetic …
[HTML][HTML] Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins
Y Han, Z Gao, L Chen, L Kang, W Huang, M **… - … Pharmaceutica Sinica B, 2019 - Elsevier
In last few years, therapeutic peptides/proteins are rapidly growing in drug market
considering their higher efficiency and lower toxicity than chemical drugs. However, the …
considering their higher efficiency and lower toxicity than chemical drugs. However, the …
An albumin-based theranostic nano-agent for dual-modal imaging guided photothermal therapy to inhibit lymphatic metastasis of cancer post surgery
A large variety of cancers are associated with a high incidence of lymph node metastasis,
which leads to a high risk of cancer death. Herein, we demonstrate that multimodal imaging …
which leads to a high risk of cancer death. Herein, we demonstrate that multimodal imaging …
Exendin‐4 analogs in insulinoma theranostics
TJP Jansen, SAM van Lith, M Boss… - Journal of Labelled …, 2019 - Wiley Online Library
Insulinomas are neuroendocrine tumors arising from the pancreatic beta cells. Currently,
surgical resection is the therapy of choice, and therefore, preoperative localization of …
surgical resection is the therapy of choice, and therefore, preoperative localization of …
Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs
The influence of nanoparticle (NP) formulations on the pharmacokinetic, pharmacodynamic
and biodistribution profiles of peptide-and protein-like drugs following oral administration is …
and biodistribution profiles of peptide-and protein-like drugs following oral administration is …
PEG-PGA enveloped octaarginine-peptide nanocomplexes: an oral peptide delivery strategy
Z Niu, E Samaridou, E Jaumain, J Coëne… - Journal of controlled …, 2018 - Elsevier
The objective of this work was the development of a new drug nanocarrier intended to
overcome the barriers associated to the oral modality of administration and to assess its …
overcome the barriers associated to the oral modality of administration and to assess its …