Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their
cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only …

Background Systemic low-grade inflammation observed in diet-induced obesity has been
associated with dysbiosis and disturbance of intestinal homeostasis. This latter relies on an …

Digested dietary fats are taken up by enterocytes where they are assembled into pre-
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …

The incidence of obesity and associated metabolic diseases is increasing globally,
adversely affecting human health. Dietary fats, especially triglycerides, are an important …

Rapid and efficient digestion and absorption of dietary triglycerides and other lipids by the
intestine, the packaging of those lipids into lipoprotein chylomicron (CM) particles, and their …

White adipose tissue and brown adipose tissue (WAT and BAT) regulate fatty acid
metabolism and control lipid fluxes to other organs. Dysfunction of these key metabolic …

In this chapter, intestinal lipid transport, which plays a central role in fat homeostasis and the
development of obesity in addition to the mechanisms of fatty acids and monoacylglycerol …

Enteroendocrine cells (EECs) in the intestine regulate many aspects of whole-body
physiology and metabolism. EECs sense luminal and circulating nutrients and respond by …

Background It is increasingly recognized that intestinal cells can store lipids after a meal, yet
the effect of this phenomenon on lipid absorption patterns in insulin resistance remains …

Context A portion of ingested fats are retained in the intestine for many hours before they are
mobilized and secreted in chylomicron (CM) particles. Factors such as glucagon-like peptide …