N-glycolylneuraminic acid (Neu5Gc), and its precursor N-acetylneuraminic acid (Neu5Ac),
commonly referred to as sialic acids, are two of the most common glycans found in …

Serine-rich-repeat proteins (SRRPs) are large mucin-like glycoprotein adhesins expressed
by a plethora of pathogenic and symbiotic Gram-positive bacteria. SRRPs play major …

Animals selectively acquire specific symbiotic gut bacteria from their environments that aid
host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut …

Background The human mouth is a natural laboratory for studying how bacterial
communities differ across habitats. Different bacteria colonize different surfaces in the mouth …

Streptococcus oralis, belonging to the viridans group streptococci (VGS), has been
considered a member of normal flora mainly inhabiting the oral cavity. However, more …

Glycosylation of proteins, previously thought to be absent in prokaryotes, is increasingly
recognized as important for both bacterial colonization and pathogenesis. For mucosal …

Bacterial binding to platelets is a key step in the development of infective endocarditis (IE).
Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for …

Bacterial binding to host receptors underlies both commensalism and pathogenesis. Many
streptococci adhere to protein-attached carbohydrates expressed on cell surfaces using …

Streptococcus oralis is an oral commensal and opportunistic pathogen that can enter the
bloodstream and cause bacteremia and infective endocarditis. Here, we investigated the …

Early detection of specific oral bacterial species would enable timely treatment and
prevention of certain oral diseases. In this work, we investigated the sensitivity and …