Consensus guidance for monitoring individuals with islet autoantibody–positive pre-stage 3 type 1 diabetes
Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …
[PDF][PDF] ISPAD Clinical Practice Consensus Guidelines 2022: Stages of type 1 diabetes in children and adolescents.
ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and
adolescents Page 1 ISPAD GUIDELINES ISPAD clinical practice consensus guidelines 2022 …
adolescents Page 1 ISPAD GUIDELINES ISPAD clinical practice consensus guidelines 2022 …
Type 1 diabetes
Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic β
cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced …
cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced …
Predictors of the initiation of islet autoimmunity and progression to multiple autoantibodies and clinical diabetes: the TEDDY study
OBJECTIVE To distinguish among predictors of seroconversion, progression to multiple
autoantibodies and from multiple autoantibodies to type 1 diabetes in young children …
autoantibodies and from multiple autoantibodies to type 1 diabetes in young children …
Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories
Abstract Development of islet autoimmunity precedes the onset of type 1 diabetes in
children, however, the presence of autoantibodies does not necessarily lead to manifest …
children, however, the presence of autoantibodies does not necessarily lead to manifest …
Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study
Background Early prediction of childhood type 1 diabetes reduces ketoacidosis at diagnosis
and provides opportunities for disease prevention. However, only highly efficient …
and provides opportunities for disease prevention. However, only highly efficient …
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes
AEJ Hendriks, ML Marcovecchio… - Diabetes/Metabolism …, 2024 - Wiley Online Library
Abstract Background/Aim Type 1 diabetes is an autoimmune disease that involves the
development of autoantibodies against pancreatic islet beta‐cell antigens, preceding clinical …
development of autoantibodies against pancreatic islet beta‐cell antigens, preceding clinical …
Islet cells in human type 1 diabetes: from recent advances to novel therapies–a symposium-based roadmap for future research
There is a growing understanding that the early phases of type 1 diabetes (T1D) are
characterised by a deleterious dialogue between the pancreatic beta cells and the immune …
characterised by a deleterious dialogue between the pancreatic beta cells and the immune …
[HTML][HTML] Multiplex agglutination-PCR (ADAP) autoantibody assays compared to radiobinding autoantibodies in type 1 diabetes and celiac disease
A Lind, F de Jesus Cortez, A Ramelius… - Journal of …, 2022 - Elsevier
Abstract Multiplex Antibody-Detection by Agglutination-PCR (ADAP) assay was compared to
singleplex standard radiobinding assays (RBA) to detect autoantibodies against insulin …
singleplex standard radiobinding assays (RBA) to detect autoantibodies against insulin …
Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes
MK Hirvonen, N Lietzén, R Moulder, SD Bhosale… - Scientific Reports, 2023 - nature.com
Better understanding of the early events in the development of type 1 diabetes is needed to
improve prediction and monitoring of the disease progression during the substantially …
improve prediction and monitoring of the disease progression during the substantially …