Liquid chromatography (LC) hyphenated to mass spectrometry is currently the most widely
used means of determining metabolic phenotypes via both untargeted and targeted …

Metabolomics represents the global assessment of metabolites in a biological sample and
reports the closest information to the phenotype of the biological system under study …

Liver toxicity is a leading systemic toxicity of drugs and chemicals demanding more human-
relevant, high throughput, cost effective in vitro solutions. In addition to contributing to animal …

Metabolomics, the comprehensive analysis of metabolites in a biological system, provides
detailed information about the biochemical/physiological status of a biological system, and …

Metabolomics use in toxicology is rapidly increasing, particularly owing to advances in mass
spectroscopy, which is widely used in the life sciences for phenoty** disease states …

Mitochondria house many metabolic pathways required for homeostasis and growth. To
explore how human cells respond to mitochondrial dysfunction, we performed metabolomics …

The analysis of metabolites in human body fluids remains a challenge because of their
chemical diversity and dynamic concentration range. Liquid chromatography (LC) in …

Green Toxicology refers to the application of predictive toxicology in the sustainable
development and production of new less harmful materials and chemicals, subsequently …

Fluctuations in oxygen tension during tissue remodeling impose a major metabolic
challenge in human tumors. Stem-like tumor cells in glioblastoma, the most common …

Read-across is a data gap filling technique used within category and analogue approaches.
It has been utilized as an alternative approach to address information requirements under …