Factors associated with rates of HBsAg seroclearance in adults with chronic HBV infection: a systematic review and meta-analysis

YH Yeo, HJ Ho, HI Yang, TC Tseng, T Hosaka… - Gastroenterology, 2019 - Elsevier
Background & Aims Seroclearance of hepatitis B surface antigen (HBsAg) is a marker for
clearance of chronic hepatitis B virus (HBV) infection, but reported annual incidence rates of …

Spontaneous loss of surface antigen among adults living with chronic hepatitis B virus infection: a systematic review and pooled meta-analyses

K Zhou, C Contag, E Whitaker… - … lancet Gastroenterology & …, 2019 - thelancet.com
Summary Background Spontaneous loss of HBsAg (known as functional cure) in patients
with chronic hepatitis B virus (HBV) infection significantly reduces liver-related …

Systematic review with meta‐analysis: development of hepatocellular carcinoma in chronic hepatitis B patients with hepatitis B surface antigen seroclearance

F Liu, XW Wang, L Chen, P Hu, H Ren… - Alimentary …, 2016 - Wiley Online Library
Background The seroclearance of hepatitis B surface antigen (HB sAg) in patients with
chronic hepatitis B (CHB) is considered to be associated with favourable clinical outcomes …

Durability of hepatitis B surface antigen seroclearance and subsequent risk for hepatocellular carcinoma: a meta‐analysis

A Song, X Wang, J Lu, Y **, L Ma, Z Hu… - Journal of Viral …, 2021 - Wiley Online Library
Hepatitis B surface antigen (HBsAg) seroclearance is regarded as the ideal endpoint for
antiviral treatment. However, reports on the durability of and outcomes after HBsAg …

Systematic review with meta‐analysis: the impact of functional cure on clinical outcomes in patients with chronic hepatitis B

A Vittal, D Sharma, A Hu, NA Majeed… - Alimentary …, 2022 - Wiley Online Library
Background Although hepatitis B surface antigen (HBsAg) loss is considered the ideal
therapeutic endpoint for the treatment of chronic hepatitis B virus (HBV) infection, its impact …

[HTML][HTML] Hepatocellular carcinoma in hepatitis B virus-infected patients and the role of hepatitis B surface antigen (HBsAg)

SP Kaur, A Talat, H Karimi-Sari, A Grees… - Journal of clinical …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading
cause of cancer-related death worldwide. Hepatitis B virus (HBV) infection is among the …

Systematic review of risk factors of hepatocellular carcinoma after hepatitis B surface antigen seroclearance

XJ Kuang, RR Jia, RR Huo, JJ Yu… - Journal of Viral …, 2018 - Wiley Online Library
There is no consensus about factors that increase risk of hepatocellular carcinoma (HCC)
among patients with chronic hepatitis B who have achieved seroclearance of hepatitis B …

[HTML][HTML] Air pollution impede ALT normalization in chronic hepatitis B patients treated with nucleotide/nucleoside analogues

TY Jang, CC Ho, CD Wu, CY Dai, PC Chen - Medicine, 2023 - journals.lww.com
Biochemical response is an important prognostic indicator in chronic hepatitis B (CHB)
patients receiving nucleotide/nucleoside analogues (NAs). However, the effects of air …

Functional cure for chronic hepatitis B: accessibility, durability, and prognosis

A Song, X Lin, X Chen - Virology journal, 2021 - Springer
Hepatitis B surface antigen (HBsAg) clearance is regarded as the ideal endpoint for antiviral
treatment in terms of drug withdrawal safety and improvements in prognosis. However, the …

Single-cell RNA-sequencing of virus-specific cellular immune responses in chronic hepatitis B patients

K Hatje, T Kam-Thong, N Giroud, A Saviano… - Scientific Data, 2024 - nature.com
Chronic hepatitis B (CHB) is a major global health challenge. CHB can be controlled by
antivirals but a therapeutic cure is lacking. CHB is characterized by limited HBV-specific T …