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Latency and lytic replication in Epstein–Barr virus-associated oncogenesis
C Münz - Nature Reviews Microbiology, 2019 - nature.com
Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is
primarily associated with lymphomas and epithelial cell cancers. These tumours express …
primarily associated with lymphomas and epithelial cell cancers. These tumours express …
Epstein–Barr virus and cancer
PJ Farrell - Annual Review of Pathology: Mechanisms of …, 2019 - annualreviews.org
Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide,
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …
Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors
A Kacen, A Javitt, MP Kramer, D Morgenstern… - Nature …, 2023 - nature.com
Post-translational modification (PTM) of antigens provides an additional source of
specificities targeted by immune responses to tumors or pathogens, but identifying antigen …
specificities targeted by immune responses to tumors or pathogens, but identifying antigen …
Epstein–Barr virus: more than 50 years old and still providing surprises
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …
discovered. EBV has subsequently been found to be associated with a diverse range of …
Hodgkin lymphoma
Hodgkin lymphoma (HL) is a B cell lymphoma characterized by few malignant cells and
numerous immune effector cells in the tumour microenvironment. The incidence of HL is …
numerous immune effector cells in the tumour microenvironment. The incidence of HL is …
Familial predisposition and genetic risk factors for lymphoma
Our understanding of familial predisposition to lymphoma (collectively defined as non-
Hodgkin lymphoma [NHL], Hodgkin lymphoma [HL], and chronic lymphocytic leukemia …
Hodgkin lymphoma [NHL], Hodgkin lymphoma [HL], and chronic lymphocytic leukemia …
Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment
Hodgkin's lymphoma (HL) represents the most common subtype of malignant lymphoma in
young people in the Western world. Most patients can be cured with modern treatment …
young people in the Western world. Most patients can be cured with modern treatment …
Epstein-Barr virus: an important vaccine target for cancer prevention
JI Cohen, AS Fauci, H Varmus, GJ Nabel - Science translational …, 2011 - science.org
Participants at the February 2011 meeting at the US National Institutes of Health on Epstein-
Barr virus (EBV) vaccine research recommend that future clinical trials have two goals …
Barr virus (EBV) vaccine research recommend that future clinical trials have two goals …
An etiological role for the Epstein-Barr virus in the pathogenesis of classical Hodgkin lymphoma
Although a pathogenic role for the Epstein-Barr virus (EBV) is largely undisputed for tumors
that are consistently EBV genome positive (eg, nasopharyngeal carcinoma, endemic Burkitt …
that are consistently EBV genome positive (eg, nasopharyngeal carcinoma, endemic Burkitt …
Epstein-Barr virus and multiple sclerosis: interaction with HLA
E Sundqvist, P Sundström, M Lindén, AK Hedström… - Genes & …, 2012 - nature.com
Epstein-Barr virus (EBV) infection, history of infectious mononucleosis (IM) and HLA-A and
DRB1 have all been proposed as risk factors for multiple sclerosis (MS). Our aim was to …
DRB1 have all been proposed as risk factors for multiple sclerosis (MS). Our aim was to …