Epileptogenesis in infants with tuberous sclerosis complex (TSC) is a gradual and dynamic
process, leading to early onset and difficult-to-treat seizures. Several cellular, molecular and …

There are no pharmacological interventions to prevent the development of epilepsy,
although many promising compounds have been identified in the animal laboratory. Clinical …

Postmortem studies have revealed increased density of excitatory synapses in the brains of
individuals with autism spectrum disorder (ASD), with a putative link to aberrant mTOR …

Tuberous sclerosis complex (TSC) is a genetic neurocutaneous disorder with epilepsy as a
common and early presenting symptom. The neurological phenotype, however, is variable …

Mutations in TSC1 or TSC2 genes are linked to alterations in neuronal function which
ultimately lead to the development of a complex neurological phenotype. Here we review …

Objective Approximately 50% of patients with tuberous sclerosis complex develop infantile
spasms, a sudden onset epilepsy syndrome associated with poor neurological outcomes …

Tuberous sclerosis complex (TSC) is a neurogenetic disorder that affects multiple organ
systems, including the heart, kidneys, eyes, skin, and central nervous system. The …

Epilepsy is one of the common brain disorders. Traditional seizure detection is done by
electroencephalography (EEG) technicians, which takes a lot of time. Therefore, this paper …

With the increasment of epilepsy patients, traditional epileptic seizure recognition is
generally completed by encephalography (EEG) technicians, which is time-consuming and …

Objective Epilepsy diagnosis can be difficult in the absence of interictal epileptic discharges
(IED) on scalp EEG. We used high-density EEG to measure connectivity in large‐scale …