Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Selective targeting of cancer cells by copper ionophores: an overview

V Oliveri - Frontiers in molecular biosciences, 2022 - frontiersin.org
Conventional cancer therapies suffer from severe off-target effects because most of them
target critical facets of cells that are generally shared by all rapidly proliferating cells. The …

Biomedicine meets Fenton chemistry

Z Tang, P Zhao, H Wang, Y Liu, W Bu - Chemical reviews, 2021 - ACS Publications
Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …

Photothermally triggered copper payload release for cuproptosis‐promoted cancer synergistic therapy

J Zhou, Q Yu, J Song, S Li, XL Li, B Kang… - Angewandte Chemie …, 2023 - Wiley Online Library
Cuproptosis is a new form of programmed cell death and exhibits enormous potential in
cancer treatment. However, reducing the undesirable Cu ion release in normal tissue and …

Recent trends of mesoporous silica-based nanoplatforms for nanodynamic therapies

Q Xu, Y Yang, J Lu, Y Lin, S Feng, X Luo, D Di… - Coordination Chemistry …, 2022 - Elsevier
Nanodynamic therapies that generate free radicals/reactive oxygen species (ROS) in situ
have the possibility to treat deep-seated tumors and have gradually become attractive …

MnOOH-catalyzed autoxidation of glutathione for reactive oxygen species production and nanocatalytic tumor innate immunotherapy

P Zhu, Y Pu, M Wang, W Wu, H Qin… - Journal of the American …, 2023 - ACS Publications
The antioxidant system, signed with reduced glutathione (GSH) overexpression, is the key
weapon for tumor to resist the attack by reactive oxygen species (ROS). Counteracting the …

Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Polypyrrole nanoenzymes as tumor microenvironment modulators to reprogram macrophage and potentiate immunotherapy

W Zeng, M Yu, T Chen, Y Liu, Y Yi, C Huang… - Advanced …, 2022 - Wiley Online Library
Nanozyme‐based tumor catalytic therapy has attracted widespread attention in recent years,
but its therapeutic outcome is drastically diminished by species of nanozyme, concentration …

A “closed‐loop” therapeutic strategy based on mutually reinforced ferroptosis and immunotherapy

Y Du, R Zhang, J Yang, S Liu, J Zhou… - Advanced Functional …, 2022 - Wiley Online Library
The immunosuppression and immune escape of current immunotherapy result in low
efficacy, and ferroptosis is greatly restricted by the low reactive oxygen species (ROS) …

Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy

H Tian, M Zhang, G **, Y Jiang, Y Luan - Journal of Colloid and Interface …, 2021 - Elsevier
Chemodynamic therapy (CDT) utilizes Fenton catalysts to convert intracellular hydrogen
peroxide (H 2 O 2) into cytotoxic hydroxyl radical (OH∙) for tumor therapy, but endogenous H …