Multicomponent solid forms of low molecular weight drugs, such as co-crystals, salts, and co-
amorphous systems, are a result of the combination of an active pharmaceutical ingredient …

Due to the poor efficacy and environmental contamination caused by the ease of leaching,
highly water-soluble herbicides have received considerable attention. For example …

In this work, the cocrystallization approach was applied to itraconazole (ITR), a very slightly
soluble triazole antifungal drug, which led to the formation of two new solid forms of ITR with …

In this study, the cocrystal of Fluconazole (FLZ) with 2‑chloro-5-nitrobenzoic acid (CNB) was
investigated through various analytical and computational techniques. One molecule of …

Amorphous solids have been widely used to improve the solubility and oral bioavailability of
poorly water-soluble drugs. Biocompatible polymeric materials are usually incorporated into …

Crystal engineering is one green alternative to organic synthesis that can be used to
manipulate molecular behavior promptly and economically. We report the preparation and …

Control over polymorphism and solvatomorphism in API assisted by structural information,
eg, molecular conformation or associations via hydrogen bonds, is crucial for the industrial …

In this work, four novel pharmaceutical cocrystals of nitrofurantoin, an antibacterial drug, with
isonicotinamide, picolinamide, 2-hydroxybenzamide, and 2-aminobenzamide have been …

The issue of poor aqueous solubility is a major hurdle in pharmaceutical dosage form
design. A large number of active molecules in the research and development pipeline …

In this study, we report the synthesis of a new organic–inorganic molecular salt of the
clinically used antifungal drug fluconazole,(H2Fluconazole). SnCl6. 2H2O. By detailed …