Spatial transcriptomics technology in cancer research
In recent years, spatial transcriptomics (ST) technologies have developed rapidly and have
been widely used in constructing spatial tissue atlases and characterizing spatiotemporal …
been widely used in constructing spatial tissue atlases and characterizing spatiotemporal …
The promise and challenge of spatial omics in dissecting tumour microenvironment and the role of AI
RY Lee, CW Ng, MP Rajapakse, N Ang… - Frontiers in …, 2023 - frontiersin.org
Growing evidence supports the critical role of tumour microenvironment (TME) in tumour
progression, metastases, and treatment response. However, the in-situ interplay among …
progression, metastases, and treatment response. However, the in-situ interplay among …
A review on deep learning applications in highly multiplexed tissue imaging data analysis
Since its introduction into the field of oncology, deep learning (DL) has impacted clinical
discoveries and biomarker predictions. DL-driven discoveries and predictions in oncology …
discoveries and biomarker predictions. DL-driven discoveries and predictions in oncology …
A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD)
Alzheimer's Disease (AD) pathology has been increasingly explored through single-cell and
single-nucleus RNA-sequencing (scRNA-seq & snRNA-seq) and spatial transcriptomics …
single-nucleus RNA-sequencing (scRNA-seq & snRNA-seq) and spatial transcriptomics …
ssREAD: A Single-cell and Spatial RNA-seq Database for Alzheimer's Disease
Alzheimer's Disease (AD) is a neurodegenerative malady predominantly affecting the
elderly and exhibits its debilitating effects on a dementia-prone population. Recently, the …
elderly and exhibits its debilitating effects on a dementia-prone population. Recently, the …
SORBET: Automated cell-neighborhood analysis of spatial transcriptomics or proteomics for interpretable sample classification via GNN
S Shimonov, JM Cunningham, R Talmon, L Aizenbud… - bioRxiv, 2024 - biorxiv.org
Spatially resolved transcriptomics or proteomics data have the potential to contribute
fundamental insights into the mechanisms underlying physiologic and pathological …
fundamental insights into the mechanisms underlying physiologic and pathological …