Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases
SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …
health and homeostasis. Although white adipose tissue and brown adipose tissue are …
New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …
proteins (RBPs) have been discovered in recent years, and the interaction between long …
LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 …
C Zhou, C Yi, Y Yi, W Qin, Y Yan, X Dong, X Zhang… - Molecular cancer, 2020 - Springer
Background Pancreatic cancer is one of the most lethal malignancies and has an extremely
poor diagnosis and prognosis. The development of resistance to gemcitabine is still a major …
poor diagnosis and prognosis. The development of resistance to gemcitabine is still a major …
Long noncoding RNAs in cancer pathways
AM Schmitt, HY Chang - Cancer cell, 2016 - cell.com
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional
mutations within the noncoding genome, with profound effects on the expression of long …
mutations within the noncoding genome, with profound effects on the expression of long …
Molecular events in neuroendocrine prostate cancer development
Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. NEPC arises
de novo only rarely; the disease predominantly develops from adenocarcinoma in response …
de novo only rarely; the disease predominantly develops from adenocarcinoma in response …
The functions and unique features of LncRNAs in cancer development and tumorigenesis
K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter”
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer
MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …
players in gene regulation. They are often differentially expressed and widely-associated …
HOTAIR: an oncogenic long non-coding RNA in human cancer
Q Tang, SS Hann - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Long non-coding RNAs (LncRNAs) represent a novel class of noncoding RNAs that
are longer than 200 nucleotides without protein-coding potential and function as novel …
are longer than 200 nucleotides without protein-coding potential and function as novel …
Long non-coding RNAs regulate drug resistance in cancer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …