Substituted Maleimides: Self‐Reportable Linkers and Tags in Bioconjugation, Materials Science, and Nanotechnology

JE Barker, JD Tibbetts, CTJ Ferguson… - Angewandte Chemie …, 2024 - Wiley Online Library
Substituted maleimides are customisable fluorescent linkers and probes with adaptable
reactivity and optical properties. Their compact nature and tunability has led to their use in …

Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective

DE Nayab, F Din, H Ali, WA Kausar, S Urooj… - Journal of …, 2023 - Springer
Neurons and their connecting axons gradually degenerate in neurodegenerative diseases
(NDs), leading to dysfunctionality of the neuronal cells and eventually their death. Drug …

Effect of heterogeneous and homogeneous polymerisation on the structure of pNIPAm nanogels

A Vdovchenko, AK Pearce, M Freeley, RK O'Reilly… - Polymer …, 2021 - pubs.rsc.org
The thermoresponsive behaviour of cross-linked poly (N-isopropylacrylamide)(pNIPAm)
nanogels makes these materials particularly attractive for a variety of applications. Literature …

Recent advances in the study of toxicity of polymer-based nanomaterials

AS Prabha, R Dorothy, S Jancirani, S Rajendran… - Nanotoxicity, 2020 - Elsevier
Polymeric nanoparticles (NPs) are colloidal particles with size ranging from 1 to 1000 nm.
They are comprised of active pharmaceutical ingredients that are within/adsorbed …

Nanomaterials in neural‐stem‐cell‐mediated regenerative medicine: Imaging and treatment of neurological diseases

B Zhang, W Yan, Y Zhu, W Yang, W Le… - Advanced …, 2018 - Wiley Online Library
Patients are increasingly being diagnosed with neuropathic diseases, but are rarely cured
because of the loss of neurons in damaged tissues. This situation creates an urgent clinical …

Sustainable and Surfactant-Free Synthesis of Negatively Charged Acrylamide Nanogels for Biomedical Applications

D Mazzali, G Rath, A Röntgen… - …, 2024 - ACS Publications
Nanogels offer unique advantages, like high surface-to-volume ratio, scalable synthetic
methods, and easily tailored formulations, that allow us to control size and introduce stimuli …

Protein-nanoparticle interactions govern the interfacial behavior of polymeric nanogels: study of protein corona formation at the air/water interface

F Traldi, P Liu, I Albino, L Ferreira, A Zarbakhsh… - International Journal of …, 2023 - mdpi.com
Biomedical applications of nanoparticles require a fundamental understanding of their
interactions and behavior with biological interfaces. Protein corona formation can alter the …

The therapeutic contribution of nanomedicine to treat neurodegenerative diseases via neural stem cell differentiation

D Carradori, J Eyer, P Saulnier, V Préat, A Des Rieux - Biomaterials, 2017 - Elsevier
The discovery of adult neurogenesis drastically changed the therapeutic approaches of
central nervous system regenerative medicine. The stimulation of this physiologic process …

The Role of Crosslinker Content of Positively Charged NIPAM Nanogels on the In Vivo Toxicity in Zebrafish

R Bilardo, F Traldi, CH Brennan, M Resmini - Pharmaceutics, 2023 - mdpi.com
Polymeric nanogels as drug delivery systems offer great advantages, such as high
encapsulation capacity and easily tailored formulations; however, data on biocompatibility …

Recent review of the effect of nanomaterials on stem cells

X Zhou, L Yuan, C Wu, G Luo, J Deng, Z Mao - RSC advances, 2018 - pubs.rsc.org
The field of stem-cell-therapy offers considerable promise as a means of delivering new
treatments for a wide range of diseases. Recent progress in nanotechnology has stimulated …