[HTML][HTML] Shifting the Paradigm: The Transformative Role of Neoadjuvant Therapy in Early Breast Cancer
N Hirmas, J Holtschmidt, S Loibl - Cancers, 2024 - mdpi.com
Simple Summary Neoadjuvant therapy, used before surgery, is an important part of breast
cancer treatment. Not only can it shrink tumors, but it can also provide valuable information …
cancer treatment. Not only can it shrink tumors, but it can also provide valuable information …
Targeting molecular pathways to control immune checkpoint inhibitor toxicities
Immune checkpoint inhibitors (ICIs) have transformed cancer treatment but are frequently
associated with immune-related adverse events (irAEs). This article offers a novel synthesis …
associated with immune-related adverse events (irAEs). This article offers a novel synthesis …
Associations between immune-related adverse events and prognosis in cancer patients receiving immune checkpoint inhibitor therapy
Y Inoue, N Inui - Internal Medicine, 2024 - jstage.jst.go.jp
The number of patients with cancer qualifying for treatment with immune checkpoint
inhibitors (ICIs) continues to increase, and a clearer understanding of the mechanisms …
inhibitors (ICIs) continues to increase, and a clearer understanding of the mechanisms …
Case report: Multi-organ injuries induced by tislelizumab
M Yuan, N Han, L Shu, L Yan, H Tang - Frontiers in Immunology, 2025 - frontiersin.org
The use of immune checkpoint inhibitors (ICIs) often develops immune-related adverse
events (irAEs). However, irAEs-induced multi-organ injuries remain a rare event. We herein …
events (irAEs). However, irAEs-induced multi-organ injuries remain a rare event. We herein …
ctDNA-guided adjuvant immunotherapy in colorectal cancer
N Burley, Y Lee, L Liu, A Gangi, Y Nasseri… - …, 2024 - Taylor & Francis
Circulating tumor DNA (ctDNA) represents a powerful measure of minimal residual disease
(MRD) in colorectal cancer (CRC). Although immunotherapy has been widely established in …
(MRD) in colorectal cancer (CRC). Although immunotherapy has been widely established in …
Oncogenic ACSM6 impairs CD8+ T cell-based immune response in bladder cancer
Z Nie, B Liu, J Liu, X Zu, J Wang, J Chen, B Fan… - Biomarker …, 2024 - Springer
Resistance to immunotherapy in bladder cancer has greatly limited its clinical application.
Through single-cell sequencing, we determined that ACSM6, an oncogene that is highly …
Through single-cell sequencing, we determined that ACSM6, an oncogene that is highly …
Fatal rhabdomyolysis and fulminant myocarditis with malignant arrhythmias after one dose of ipilimumab and nivolumab
M Kurnik, P Kolar Kus, M Krepek, J Vlaović… - …, 2024 - Taylor & Francis
Immune checkpoint inhibitors (ICIs) related myocarditis is a rare complication of modern
immunotherapy. It can present as an asymptomatic subclinical condition or full-blown …
immunotherapy. It can present as an asymptomatic subclinical condition or full-blown …
Reply to: Peak Corticosteroid Dose for Immune-Related Adverse Events and Survival: Not the Whole Story
RJ Verheijden, JS de Groot, BO Fabriek… - Journal of Clinical …, 2024 - ascopubs.org
We read with interest the correspondence by Guven 1 regarding our manuscript 2 in which
we reported that higher corticosteroid peak dose to treat immune-related adverse events …
we reported that higher corticosteroid peak dose to treat immune-related adverse events …
Exploring Immune-Related Adverse Events: Real-World Insights from 2523 PD-1/PD-L1 Inhibitor Patients
T Yan, M Long, C Liu, J Zhang, X Wei, F Li… - Frontiers in … - frontiersin.org
Immune checkpoint inhibitors (ICIs) have significantly changed cancer therapy, improving
patient survival rates and clinical outcomes. Nevertheless, the use of PD-1/PD-L1 inhibitors …
patient survival rates and clinical outcomes. Nevertheless, the use of PD-1/PD-L1 inhibitors …
Antitumor effects and immune‐mediated adverse events of durvalumab plus tremelimumab treatment for unresectable hepatocellular carcinoma
T Ito, S Shimose, J Tani, T Tomonari, I Saeki… - Hepatology … - Wiley Online Library
Abstract Aim Durvalumab plus tremelimumab (Dur/Tre) is a first‐line systemic treatment
option for unresectable hepatocellular carcinoma (uHCC). However, the management of …
option for unresectable hepatocellular carcinoma (uHCC). However, the management of …