Time-lapse, deep-tissue imaging made possible by advances in intravital microscopy has
demonstrated the importance of tumour cell migration through confining tracks in vivo. These …

Chemical and physical properties of the environment control cell proliferation, differentiation,
or apoptosis in the long term. However, to be able to move and migrate through a complex …

There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Immune responses rely on the rapid and coordinated migration of leukocytes. Whereas it is
well established that single-cell migration is often guided by gradients of chemokines and …

The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

The directed migration of cell collectives is essential in various physiological processes,
such as epiboly, intestinal epithelial turnover, and convergent extension during …

Growing evidence suggests that the physical properties of the cellular microenvironment
influence cell migration. However, it is not currently understood how active physical …

Arabidopsis thaliana cryptochrome 2 (At CRY2), a light-sensitive photosensory protein, was
previously adapted for use in controlling protein–protein interactions through light …

Migration of leukocytes is essential for the induction, maintenance, and regulation of
immune responses. On their trafficking routes, leukocytes encounter microenvironments of …

Motile cells have developed a variety of migration modes relying on diverse traction-force-
generation mechanisms. Before the behavior of intracellular components could be easily …