[HTML][HTML] Naphthoquinones as a promising class of compounds for facing the challenge of Parkinson's disease

TB Santos, LGC de Moraes, PAF Pacheco… - Pharmaceuticals, 2023 - mdpi.com
Parkinson's disease (PD) is a degenerative disease that affects approximately 6.1 million
people and is primarily caused by the loss of dopaminergic neurons. Naphthoquinones …

[HTML][HTML] Inspired by sea urchins: Warburg effect mediated selectivity of novel synthetic non-glycoside 1, 4-naphthoquinone-6S-glucose conjugates in prostate cancer

SA Dyshlovoy, DN Pelageev, J Hauschild, YE Sabutskii… - Marine Drugs, 2020 - mdpi.com
The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It
results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in …

Direct Lawsone O-Alkylation Employing Sulfonic Acid-Functionalized Chitosan as a Biodegradable Organocatalyst

IS de Jesus, J Baptista de Pontes, VMF Paschoalin… - ACS …, 2025 - ACS Publications
An environmentally friendly, cheap, and scalable protocol for direct lawsone O-alkylation
employing different alcohols using acid chitosan (CS–SO3H) as a heterogeneous …

Synthesis, Cytotoxic Activity Evaluation and Quantitative Structure-ActivityAnalysis of Substituted 5,8-Dihydroxy-1,4-naphthoquinones and Their O- and S-Glycoside …

S Polonik, G Likhatskaya, Y Sabutski, D Pelageev… - Marine Drugs, 2020 - mdpi.com
Based on 6, 7-substituted 2, 5, 8-trihydroxy-1, 4-naphtoquinones (1, 4-NQs) derived from
sea urchins, five new acetyl-O-glucosides of NQs were prepared. A new method of …

A simple synthesis of natural spinazarins and their analogues

DN Pelageev, KL Borisova, SM Kovach… - Mendeleev …, 2023 - Elsevier
A short simple synthesis of spinazarins (2, 3-dihydroxy-naphthazarins or 2, 3, 5, 8-
tetrahydroxy-1, 4-naphtho-quinones) from available 2, 3-dichloronaphthazarin derivatives …

[PDF][PDF] SYNTHESIS OF NATURAL QUINOID COMPOUNDS AND THEIR ANALOGUES BASED ON AZIDO DERIVATIVES OF NAPHTHAZARIN

DN Pelageev - LBC 94.3 T44, 2022 - biosoil.ru
Natural polyhydroxylated naphthazarins (5, 8-dihydroxy-1, 4-naphthoquinones) are a group
of compounds found in echinoderms and lichens [1]. Due to the wide range of biological …