Transcription-coupled repair (TCR), discovered as preferential nucleotide excision repair of
UV-induced cyclobutane pyrimidine dimers located in transcribed mammalian genes …

The article presents the result of a study which examined DNA repair through photolyase in
Escherichia coli and nucleotide excision repair in both microorganism and humans. The …

DNA is the molecule chosen by nature to store the information required to build organisms.
These organisms in turn serve to replicate that information. It was initially thought that DNA …

The relationship between protein three-dimensional structure and function is essential for
mechanism determination. Unfortunately, most techniques do not provide a direct …

One of the best-studied DNA repair pathways is nucleotide excision repair, a process
consisting of DNA damage recognition, incision, excision, repair resynthesis, and DNA …

The nucleotide excision repair (NER) pathway removes helix-distorting lesions from DNA in
all organisms. Escherichia coli has long been a model for understanding NER, which is …

Nucleotide excision repair (NER) has allowed bacteria to flourish in many different niches
around the globe that inflict harsh environmental damage to their genetic material. NER is …

Molecular motors are diverse enzymes that transduce chemical energy into mechanical
work and, in doing so, perform critical cellular functions such as DNA replication and …

Soluble extracts from human lymphoid cell lines that perform repair synthesis on covalently
closed circular DNA containing pyrimidine dimers or psoralen adducts are described. Short …

In bacteria, mutations lead to the evolution of antibiotic resistance, which is one of the main
public health problems of the twenty-first century. Therefore, determining which cellular …