The blood–brain barrier, which is formed by the endothelial cells that line cerebral
microvessels, has an important role in maintaining a precisely regulated microenvironment …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …

PURPOSE: To determine if focused ultrasound beams can be used to locally open the blood-
brain barrier without damage to surrounding brain tissue and if magnetic resonance (MR) …

Glia are essential for brain functioning during development and in the adult brain. Here, we
discuss the various roles of both microglia and astrocytes, and their interactions during brain …

The blood–brain barrier (BBB) is formed by brain endothelial cells lining the cerebral
microvasculature, and is an important mechanism for protecting the brain from fluctuations in …

The central nervous system is well protected by the blood–brain barrier (BBB) which
maintains its homeostasis. Due to this barrier many potential drugs for the treatment of …

Unlike some interfaces between the blood and the nervous system (eg, nerve perineurium),
the brain endothelium forming the blood–brain barrier can be modulated by a range of …

The blood–brain barrier (BBB) prevents entry of most drugs into the brain and is a major
hurdle to the use of drugs for brain tumors and other central nervous system disorders. Work …

The brain is a delicate organ, and evolution built very efficient ways to protect it.
Unfortunately, the same mechanisms that protect it against intrusive chemicals can also …