Thiazolidine-2, 4-diones: Progress towards multifarious applications

VS Jain, DK Vora, CS Ramaa - Bioorganic & medicinal chemistry, 2013 - Elsevier
The promising activity shown by compounds containing thiazolidine-2, 4-dione nucleus in
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …

Thiazolidin-2, 4-dione scaffold: an insight into recent advances as antimicrobial, antioxidant, and hypoglycemic agents

H Kumar, N Aggarwal, MG Marwaha, A Deep… - Molecules, 2022 - mdpi.com
Heterocyclic compounds containing nitrogen and sulfur, especially those in the thiazole
family, have generated special interest in terms of their synthetic chemistry, which is …

Novel hybrids of thiazolidinedione-1, 3, 4-oxadiazole derivatives: synthesis, molecular docking, MD simulations, ADMET study, in vitro, and in vivo anti-diabetic …

MG Srinivasa, JG Paithankar, SRS Birangal, A Pai… - RSC …, 2023 - pubs.rsc.org
As compared to standard medicinal compounds, hybrid molecules that contain multiple
biologically active functional groups have greater affinity and efficiency. Hence based on this …

Antifungal thiazolidines: Synthesis and biological evaluation of mycosidine congeners

IB Levshin, AY Simonov, SN Lavrenov, AA Panov… - Pharmaceuticals, 2022 - mdpi.com
Novel derivatives of Mycosidine (3, 5-substituted thiazolidine-2, 4-diones) are synthesized
by Knoevenagel condensation and reactions of thiazolidines with chloroformates or halo …

Antibacterial properties of 5-substituted derivatives of rhodanine-3-carboxyalkyl acids

W Tejchman, I Korona-Glowniak, A Malm… - Medicinal Chemistry …, 2017 - Springer
A series of rhodanine 3-carboxyalkanoic acid derivatives possessing 4′-(N, N-dialkyl-
amino or diphenylamino)-benzylidene moiety as a substituent at the C-5 position were …

Novel tetrazoloquinoline–rhodanine conjugates: highly efficient synthesis and biological evaluation

DD Subhedar, MH Shaikh, L Nawale, A Yeware… - Bioorganic & Medicinal …, 2016 - Elsevier
In search of new active molecules against Mycobacterium tuberculosis (MTB) H37Ra and
Mycobacterium bovis BCG, a small focused library of rhodanine incorporated …

Evaluation of thiazolidinone derivatives as a new class of mushroom tyrosinase inhibitors

M Rezaei, HT Mohammadi, A Mahdavi… - International journal of …, 2018 - Elsevier
Abstract Tyrosinase (EC 1.14. 18.1) is a key copper-containing metalloenzyme widely
distributed in nature and plays determinant role in melanin biosynthesis. The enzyme …

[HTML][HTML] Synthesis and antibacterial activity of new (2, 4-dioxothiazolidin-5-yl/ylidene) acetic acid derivatives with thiazolidine-2, 4-dione, rhodanine and 2 …

N Trotsko, U Kosikowska, A Paneth, M Wujec… - Saudi pharmaceutical …, 2018 - Elsevier
Abstract A series of new (2, 4-dioxothiazolidin-5-yl/ylidene) acetic acid derivatives with
thiazolidine-2, 4-dione, rhodanine and 2-thiohydantoin moiety (28–65) were synthesized by …

Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation

DD Subhedar, MH Shaikh, BB Shingate… - European Journal of …, 2017 - Elsevier
A series of rhodanine incorporated quinoline derivatives were efficiently synthesized using
reusable DBU acetate as ionic liquid and evaluated for their in vitro antitubercular activity …

Synthesis and biological evaluation of new rhodanine analogues bearing 2-chloroquinoline and benzo [h] quinoline scaffolds as anticancer agents

V Ramesh, BA Rao, P Sharma, B Swarna… - European Journal of …, 2014 - Elsevier
Abstract Several rhodanine derivatives (9–39) were synthesized for evaluation of their
potential as anticancer agents. Villsmeier cyclization to synthesize aza-aromatic aldehydes …