Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
The PI3K/Akt/mTOR pathway: A potential pharmacological target in COVID-19
MS Basile, E Cavalli, J McCubrey… - Drug discovery today, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) has emerged as a serious threat to global
health. The disregulation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian …
health. The disregulation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian …
Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID
M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …
Evaluation of off-label rapamycin use to promote healthspan in 333 adults
TL Kaeberlein, AS Green, G Haddad, J Hudson… - Geroscience, 2023 - Springer
Rapamycin (sirolimus) is an FDA-approved drug with immune-modulating and growth-
inhibitory properties. Preclinical studies have shown that rapamycin extends lifespan and …
inhibitory properties. Preclinical studies have shown that rapamycin extends lifespan and …
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications
COVID-19 complications still present a huge burden on healthcare systems and warrant
predictive risk models to triage patients and inform early intervention. Here, we profile 893 …
predictive risk models to triage patients and inform early intervention. Here, we profile 893 …
[HTML][HTML] Cellular senescence in immunity against infections
Cellular senescence is characterized by irreversible cell cycle arrest in response to different
triggers and an inflammatory secretome. Although originally described in fibroblasts and cell …
triggers and an inflammatory secretome. Although originally described in fibroblasts and cell …
Blocking TNF signaling may save lives in COVID-19 infection
V Ablamunits, C Lepsy - Molecular Biology Reports, 2022 - Springer
Global vaccination effort and better understanding of treatment strategies provided a ray of
hope for improvement in COVID-19 pandemic, however, in many countries, the disease …
hope for improvement in COVID-19 pandemic, however, in many countries, the disease …
The Dynamic Role of FOXP3+ Tregs and Their Potential Therapeutic Applications During SARS-CoV-2 Infection
Coronavirus disease 2019 (COVID-19) has been raging all around the world since the
beginning of 2020, and leads to acute respiratory distress syndrome (ARDS) with strong …
beginning of 2020, and leads to acute respiratory distress syndrome (ARDS) with strong …
Structural analysis of SARS-CoV-2 ORF8 protein: pathogenic and therapeutic implications
Current therapeutic strategies and vaccines against SARS-CoV-2 are mainly focused on the
Spike protein despite there are other viral proteins with important roles in COVID-19 …
Spike protein despite there are other viral proteins with important roles in COVID-19 …
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
immunocompromised individuals is associated with prolonged virus shedding and evolution …
immunocompromised individuals is associated with prolonged virus shedding and evolution …
Autophagy inducer rapamycin treatment reduces IFN-I–mediated Inflammation and improves anti–HIV-1 T cell response in vivo
A hallmark of HIV-1 infection is chronic inflammation, even in patients treated with
antiretroviral therapy (ART). Chronic inflammation drives HIV-1 pathogenesis, leading to …
antiretroviral therapy (ART). Chronic inflammation drives HIV-1 pathogenesis, leading to …