Biochemistry and theory of proton-coupled electron transfer

A Migliore, NF Polizzi, MJ Therien… - Chemical reviews, 2014 - ACS Publications
Through incremental change, Nature reworks and repurposes its functional machinery. In
this way, proteins that photochemically repair DNA by moving protons and electrons have a …

Graph-theoretic molecular fragmentation for potential surfaces leads naturally to a tensor network form and allows accurate and efficient quantum nuclear dynamics

A Kumar, N DeGregorio, T Ricard… - Journal of Chemical …, 2022 - ACS Publications
Molecular fragmentation methods have revolutionized quantum chemistry. Here, we use a
graph-theoretically generated molecular fragmentation method, to obtain accurate and …

Rare Events Sampling Methods for Quantum and Classical Ab Initio Molecular Dynamics

SS Iyengar, HB Schlegel, I Sumner… - The Journal of Physical …, 2024 - ACS Publications
We provide an approach to sample rare events during classical ab initio molecular dynamics
and quantum wavepacket dynamics. For classical AIMD, a set of fictitious degrees of …

Graph-theory-based molecular fragmentation for efficient and accurate potential surface calculations in multiple dimensions

A Kumar, N DeGregorio, SS Iyengar - Journal of Chemical Theory …, 2021 - ACS Publications
We present a multitopology molecular fragmentation approach, based on graph theory, to
calculate multidimensional potential energy surfaces in agreement with post-Hartree–Fock …

6 semiclassical bohmian dynamics

S Garashchuk, V Rassolov… - Reviews in computational …, 2011 - Wiley Online Library
Quantum mechanics lies at the heart of chemistry. It is impossible to understand the structure
of the Periodic Table, chemical bonding patterns, free energies of chemical reactions …

Hydrogen tunneling in an enzyme active site: A quantum wavepacket dynamical perspective

SS Iyengar, I Sumner, J Jakowski - The Journal of Physical …, 2008 - ACS Publications
We study the hydrogen tunneling problem in a model system that represents the active site
of the biological enzyme, soybean lipoxygenase-1. Toward this, we utilize quantum …

Insights from first principles molecular dynamics studies toward infrared multiple-photon and single-photon action spectroscopy: Case study of the proton-bound …

X Li, DT Moore, SS Iyengar - The Journal of chemical physics, 2008 - pubs.aip.org
We have used finite temperature ab initio molecular dynamics simulations in conjunction
with computation of critical quantum nuclear effects to probe the differences between single …

Quantum wavepacket ab initio molecular dynamics: An approach for computing dynamically averaged vibrational spectra including critical nuclear quantum effects

I Sumner, SS Iyengar - The Journal of Physical Chemistry A, 2007 - ACS Publications
We have introduced a computational methodology to study vibrational spectroscopy in
clusters inclusive of critical nuclear quantum effects. This approach is based on the recently …

Fragment-based electronic structure for potential energy surfaces using a superposition of fragmentation topologies

A Kumar, SS Iyengar - Journal of Chemical Theory and …, 2019 - ACS Publications
We present a new approach for adaptive molecular fragmentation. Here multiple
fragmentation protocols, or fragmentation topologies, are combined to efficiently and …

Isotope dependent, temperature regulated, energy repartitioning in a low-barrier, short-strong hydrogen bonded cluster

X Li, J Oomens, JR Eyler, DT Moore… - The Journal of chemical …, 2010 - pubs.aip.org
We investigate and analyze the vibrational properties, including hydrogen/deuterium isotope
effects, in a fundamental organic hydrogen bonded system using multiple experimental …