Dynamic mechanical compression of chondrocytes for tissue engineering: a critical review
DE Anderson, B Johnstone - Frontiers in bioengineering and …, 2017 - frontiersin.org
Articular cartilage functions to transmit and translate loads. In a classical structure–function
relationship, the tissue resides in a dynamic mechanical environment that drives the …
relationship, the tissue resides in a dynamic mechanical environment that drives the …
Development of chitosan/hyaluronic acid hydrogel scaffolds via enzymatic reaction for cartilage tissue engineering
Biomimetic hydrogels have been developed in the fabrication of multifunctional
microenvironments for cell culture and tissue fabrication. In the current study, different …
microenvironments for cell culture and tissue fabrication. In the current study, different …
Biomechanical issues of tissue-engineered constructs for articular cartilage regeneration: in vitro and in vivo approaches
Background Given the limited regenerative capacity of injured articular cartilage, the
absence of suitable therapeutic options has encouraged tissue-engineering approaches for …
absence of suitable therapeutic options has encouraged tissue-engineering approaches for …
Advances in cartilage repair: The influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels
Effective treatment of cartilage defects represents a challenging problem, mainly due to the
tissue's limited intrinsic self-repair capacity; the use of polymeric scaffolds as tissue …
tissue's limited intrinsic self-repair capacity; the use of polymeric scaffolds as tissue …
The interplay between chondrocyte spheroids and mesenchymal stem cells boosts cartilage regeneration within a 3D natural-based hydrogel
Articular cartilage (AC) lacks the ability to self-repair and cell-based approaches, primarily
based on using chondrocytes and mesenchymal stem cells (MSCs), are emerging as …
based on using chondrocytes and mesenchymal stem cells (MSCs), are emerging as …
Effect of hydration on healthy intervertebral disk mechanical stiffness
The intervertebral disk has an excellent swelling capacity to absorb water, which is thought
to be largely due to the high proteoglycan composition. Injury, aging, degeneration, and …
to be largely due to the high proteoglycan composition. Injury, aging, degeneration, and …
[HTML][HTML] Effectiveness of gellan gum scaffolds loaded with Boswellia serrata extract for in-situ modulation of pro-inflammatory pathways affecting cartilage healing
In this study, we developed a composite hydrogel based on Gellan gum containing
Boswellia serrata extract (BSE). BSE was either incorporated directly or loaded into an MgAl …
Boswellia serrata extract (BSE). BSE was either incorporated directly or loaded into an MgAl …
Novel phase separated polycaprolactone/collagen scaffolds for cartilage tissue engineering
Osteoarthritis is the leading cause of pain and disability worldwide. Despite treatment
availability, fully functional and suitable long term treatments for large cartilage defects are …
availability, fully functional and suitable long term treatments for large cartilage defects are …
High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties
Animal cells have served as highly controllable model systems for furthering cartilage tissue
engineering practices in pursuit of treating osteoarthritis. Although successful strategies for …
engineering practices in pursuit of treating osteoarthritis. Although successful strategies for …
Load-induced fluid pressurisation in hydrogel systems before and after reinforcement by melt-electrowritten fibrous meshes
Fluid pressure develops transiently within mechanically-loaded, cell-embedding hydrogels,
but its magnitude depends on the intrinsic material properties of the hydrogel and cannot be …
but its magnitude depends on the intrinsic material properties of the hydrogel and cannot be …