Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

Clinical management of metastatic colorectal cancer in the era of precision medicine

F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary, N Azad… - Journal of the National …, 2022 - jnccn.org
This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN

E Morgan, M Arnold, A Gini, V Lorenzoni, CJ Cabasag… - Gut, 2023 - gut.bmj.com
Objective Colorectal cancer (CRC) is the third most common cancer worldwide. The
geographical and temporal burden of this cancer provides insights into risk factor …

PD-1 blockade in mismatch repair–deficient, locally advanced rectal cancer

A Cercek, M Lumish, J Sinopoli, J Weiss… - … England Journal of …, 2022 - Mass Medical Soc
Background Neoadjuvant chemotherapy and radiation followed by surgical resection of the
rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is …

Current and future colorectal cancer screening strategies

A Shaukat, TR Levin - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Despite strong evidence of effectiveness, colorectal cancer (CRC) screening remains
underused. Currently, there are several options for CRC screening, each with its own …

Increasing incidence of early-onset colorectal cancer

FA Sinicrope - New England Journal of Medicine, 2022 - Mass Medical Soc
Early-Onset Colorectal Cancer Early-onset disease (at< 50 years of age) accounts for 10%
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …

Colon cancer, version 3.2024, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, M Adam, G Chang… - Journal of the National …, 2024 - jnccn.org
Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second
leading cause of cancer death in the United States. Management of disseminated metastatic …

Cancer statistics for African American/black people 2022

AN Giaquinto, KD Miller, KY Tossas… - CA: a cancer journal …, 2022 - Wiley Online Library
Abstract African American/Black individuals have a disproportionate cancer burden,
including the highest mortality and the lowest survival of any racial/ethnic group for most …

[HTML][HTML] Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis

J Cai, L Sun, FJ Gonzalez - Cell host & microbe, 2022 - cell.com
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …