Fundamental Aspects of Phase-Separated Biomolecular Condensates

HX Zhou, D Kota, S Qin, R Prasad - Chemical Reviews, 2024 - ACS Publications
Biomolecular condensates, formed through phase separation, are upending our
understanding in much of molecular, cell, and developmental biology. There is an urgent …

Liquid–liquid phase separation in plants: Advances and perspectives from model species to crops

Q Liu, W Liu, Y Niu, T Wang, J Dong - Plant Communications, 2024 - cell.com
Membraneless biomolecular condensates play important roles in both normal biological
activities and responses to environmental stimuli in living organisms. Liquid‒liquid phase …

Microscopic dynamics of liquid-liquid phase separation and domain coarsening in a protein solution revealed by X-ray photon correlation spectroscopy

A Girelli, H Rahmann, N Begam, A Ragulskaya… - Physical Review Letters, 2021 - APS
While the interplay between liquid-liquid phase separation (LLPS) and glass formation in
biological systems is highly relevant for their structure formation and thus function, the exact …

Time-Resolved Observations of Liquid–Liquid Phase Separation at the Nanoscale Using in Situ Liquid Transmission Electron Microscopy

H Le Ferrand, M Duchamp, B Gabryelczyk… - Journal of the …, 2019 - ACS Publications
Liquid–liquid phase separation (LLPS) of proteins into concentrated microdroplets (also
called coacervation) is a phenomenon that is increasingly recognized to occur in many …

Protein physical state in meat analogue processing

J Ubbink, BJ Muhialdin - Current Opinion in Food Science, 2022 - Elsevier
Highlights•Meat analog structuring is analyzed in the light of plant protein phase
behavior.•The water-content dependence of the soy 7S and 11S denaturation is …

[HTML][HTML] The mechanobiology of nuclear phase separation

DSW Lee, AR Strom, CP Brangwynne - APL bioengineering, 2022 - pubs.aip.org
The cell nucleus can be thought of as a complex, dynamic, living material, which functions to
organize and protect the genome and coordinate gene expression. These functions are …

Soft condensed matter physics of foods and macronutrients

S Assenza, R Mezzenga - Nature Reviews Physics, 2019 - nature.com
Understanding food properties is paramount for enhancing features such as appearance,
taste and texture, for improving health-related factors such as minimizing the onset of …

Glutenin and gliadin, a piece in the puzzle of their structural properties in the cell described through Monte Carlo simulations

J Markgren, M Hedenqvist, F Rasheed, M Skepö… - Biomolecules, 2020 - mdpi.com
Gluten protein crosslinking is a predetermined process where specific intra-and
intermolecular disulfide bonds differ depending on the protein and cysteine motif. In this …

[HTML][HTML] Clustering and cross-linking of the wheat storage protein α-gliadin: A combined experimental and theoretical approach

J Markgren, F Rasheed, MS Hedenqvist… - International Journal of …, 2022 - Elsevier
Our aim was to understand mechanisms for clustering and cross-linking of gliadins, a wheat
seed storage protein type, monomeric in native state, but incorporated in network while …

Soft-matter approaches for controlling food protein interactions and assembly

A Boire, D Renard, A Bouchoux… - Annual review of …, 2019 - annualreviews.org
Animal-and plant-based proteins are present in a wide variety of raw and processed foods.
They play an important role in determining the final structure of food matrices. Food proteins …