Diabetic kidney disease (DKD) is one of the fastest growing causes of chronic kidney
disease and associated morbidity and mortality. Preclinical research has demonstrated the …

Diabetic kidney disease (DKD) is becoming the leading cause of chronic kidney disease,
especially in the industrialized world. Despite mounting evidence has demonstrated that …

Neutrophil migration into the site of infection is necessary for antibacterial innate defense,
whereas impaired neutrophil migration may result in excessive inflammation and even …

Ankylosing spondylitis (AS) is a type of rheumatic disease characterized by chronic
inflammation and pathological osteogenesis in the entheses. Previously, we demonstrated …

The small GTPase Rac1 has been implicated in a variety of dynamic cell biological
processes, including cell proliferation, cell survival, cell-cell contacts, epithelial …

Endogenous DNA derived from the nuclei or mitochondria is released into the bloodstream
following cell damage or death. Extracellular DNA, called cell-free DNA (cfDNA), is …

Rheumatoid arthritis (RA) is a chronic inflammatory disease of the synovial joints that
affects~ 1% of the human population. Joint swelling and bone erosion, hallmarks of RA …

The presence of anti-citrullinated protein autoantibodies (ACPA) is a hallmark feature of
rheumatoid arthritis (RA), which causes chronic joint destruction and systemic inflammation …

Rheumatoid arthritis (RA), an autoimmune disease of unknown etiology, is a serious threat
to the health of middle-aged and elderly people. Although western medicine, traditional …

The molecular mechanisms that drive the onset and development of osteoarthritis (OA)
remain largely unknown. In this exploratory study, we used a proteomic platform (SOMAscan …