EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer. Part II—2020 update: treatment of relapsing and metastatic prostate cancer

P Cornford, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

[HTML][HTML] Current therapy and drug resistance in metastatic castration-resistant prostate cancer

M Cai, XL Song, XA Li, M Chen, J Guo, DH Yang… - Drug Resistance …, 2023 - Elsevier
Castration-resistant prostate cancer (CRPC), especially metastatic castration-resistant
prostate cancer (mCRPC) is one of the most prevalent malignancies and main cause of …

EAU-ESTRO-SIOG guidelines on prostate cancer. Part II: treatment of relapsing, metastatic, and castration-resistant prostate cancer

P Cornford, J Bellmunt, M Bolla, E Briers, M De Santis… - European urology, 2017 - Elsevier
Objective To present a summary of the 2016 version of the European Association of Urology
(EAU)–European Society for Radiotherapy & Oncology (ESTRO)–International Society of …

Addition of radium-223 to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases (ERA 223): a …

M Smith, C Parker, F Saad, K Miller, B Tombal… - The Lancet …, 2019 - thelancet.com
Background Abiraterone acetate plus prednisone or prednisolone improves progression-
free survival and overall survival in patients with metastatic castration-resistant prostate …

Targeting signaling pathways in prostate cancer: mechanisms and clinical trials

Y He, W Xu, YT **ao, H Huang, D Gu… - Signal transduction and …, 2022 - nature.com
Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Novel approaches to target the microenvironment of bone metastasis

LC Hofbauer, A Bozec, M Rauner, F Jakob… - Nature reviews Clinical …, 2021 - nature.com
Bone metastases are a frequent and severe complication of advanced-stage cancers. Breast
and prostate cancers, the most common malignancies in women and men, respectively …

Tumor microenvironment mechanisms and bone metastatic disease progression of prostate cancer

J Kang, F La Manna, F Bonollo, N Sampson, IL Alberts… - Cancer letters, 2022 - Elsevier
During disease progression from primary towards metastatic prostate cancer (PCa), and in
particular bone metastases, the tumor microenvironment (TME) evolves in parallel with the …

Epidemiology, staging and management of prostate cancer

A Barsouk, SA Padala, A Vakiti, A Mohammed… - Medical …, 2020 - mdpi.com
Prostate cancer is the second most common and fifth most aggressive neoplasm among
men worldwide. It is particularly incident in high human development index (HDI) nations …

Molecular mechanisms and clinical management of cancer bone metastasis

M Wang, F **a, Y Wei, X Wei - Bone research, 2020 - nature.com
As one of the most common metastatic sites of malignancies, bone has a unique
microenvironment that allows metastatic tumor cells to grow and flourish. The fenestrated …

The treatment landscape of metastatic prostate cancer

Y Yamada, H Beltran - Cancer letters, 2021 - Elsevier
The treatment landscape of metastatic prostate cancer has evolved significantly over the
past two decades. Several landmark phase 3 trials led to new drug approvals and rapid …