[HTML][HTML] Natural therapeutics and nutraceuticals for lung diseases: traditional significance, phytochemistry, and pharmacology

MM Rahman, S Bibi, MS Rahaman, F Rahman… - Biomedicine & …, 2022‏ - Elsevier
Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …

The lung microenvironment: an important regulator of tumour growth and metastasis

NK Altorki, GJ Markowitz, D Gao, JL Port… - Nature Reviews …, 2019‏ - nature.com
Lung cancer is a major global health problem, as it is the leading cause of cancer-related
deaths worldwide. Major advances in the identification of key mutational alterations have led …

Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing

J Hu, L Zhang, H **a, Y Yan, X Zhu, F Sun, L Sun, S Li… - Genome medicine, 2023‏ - Springer
Background Immunotherapy has revolutionized cancer treatment, but most patients are
refractory to immunotherapy or acquire resistance, with the underlying mechanisms …

[PDF][PDF] Obesity and Lung Cancer (Investigating the Relationship)

N Tzenios - EPRA International Journal of Multidisciplinary …, 2023‏ - researchgate.net
Obesity is a global issue, and it leads to various health comorbidities like cardiovascular
disease, diabetes type II and certain cancers. The relationship between obesity and cancer …

[HTML][HTML] The PI3K/Akt/mTOR pathway in lung cancer; oncogenic alterations, therapeutic opportunities, challenges, and a glance at the application of nanoparticles

MJ Sanaei, S Razi, A Pourbagheri-Sigaroodi… - Translational …, 2022‏ - Elsevier
Lung cancer is the leading cause of cancer-related mortality worldwide. Although the
PI3K/Akt/mTOR signaling pathway has recently been considered as one of the most altered …

The single-cell immunogenomic landscape of B and plasma cells in early-stage lung adenocarcinoma

D Hao, G Han, A Sinjab, LI Gomez-Bolanos… - Cancer …, 2022‏ - aacrjournals.org
Tumor-infiltrating B and plasma cells (TIB) are prevalent in lung adenocarcinoma (LUAD);
however, they are poorly characterized. We performed paired single-cell RNA and B-cell …

FAPI-74 PET/CT using either 18F-AlF or cold-kit 68Ga labeling: biodistribution, radiation dosimetry, and tumor delineation in lung cancer patients

FL Giesel, S Adeberg, M Syed… - Journal of Nuclear …, 2021‏ - jnm.snmjournals.org
68 Ga-fibroblast activation protein inhibitors (FAPIs) 2, 4, and 46 have already been
proposed as promising PET tracers. However, the short half-life of 68 Ga (68 min) creates …

Immune cell composition in human non-small cell lung cancer

B Stankovic, HAK Bjørhovde, R Skarshaug… - Frontiers in …, 2019‏ - frontiersin.org
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in the
world. Immunological analysis of the tumor microenvironment (immunoscore) shows great …

Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin

MG Oser, MJ Niederst, LV Sequist… - The Lancet …, 2015‏ - thelancet.com
Lung cancer is the most common cause of cancer deaths worldwide. The two broad
histological subtypes of lung cancer are small-cell lung cancer (SCLC), which is the cause of …

[HTML][HTML] The role of tumor-infiltrating lymphocytes in development, progression, and prognosis of non–small cell lung cancer

RM Bremnes, LT Busund, TL Kilvær, S Andersen… - Journal of Thoracic …, 2016‏ - Elsevier
A malignant tumor is not merely an accumulation of neoplastic cells, but constitutes a
microenvironment containing endothelial cells, fibroblasts, structural components, and …