Human retrovirus genomic RNA packaging
Two non-covalently linked copies of the retrovirus genome are specifically recruited to the
site of virus particle assembly and packaged into released particles. Retroviral RNA …
site of virus particle assembly and packaged into released particles. Retroviral RNA …
On the way to understanding the interplay between the RNA structure and functions in cells: a genome-wide perspective
A Andrzejewska, M Zawadzka… - International journal of …, 2020 - mdpi.com
RNAs adopt specific structures in order to perform their biological activities. The structure of
RNA is an important layer of gene expression regulation, and can impact a plethora of …
RNA is an important layer of gene expression regulation, and can impact a plethora of …
A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms
K Lepeta, KJ Purzycka… - EMBO Molecular …, 2017 - embopress.org
Abstract Matrix metalloproteinase 9 (MMP‐9) has recently emerged as a molecule that
contributes to pathological synaptic plasticity in schizophrenia, but explanation of the …
contributes to pathological synaptic plasticity in schizophrenia, but explanation of the …
RNAthor–fast, accurate normalization, visualization and statistical analysis of RNA probing data resolved by capillary electrophoresis
RNAs adopt specific structures to perform their functions, which are critical to fundamental
cellular processes. For decades, these structures have been determined and modeled with …
cellular processes. For decades, these structures have been determined and modeled with …
[HTML][HTML] Identification of Pr78Gag binding sites on the Mason-Pfizer monkey virus genomic RNA packaging determinants
How retroviral Gag proteins recognize the packaging signals (Psi) on their genomic RNA
(gRNA) is a key question that we addressed here using Mason-Pfizer monkey virus (MPMV) …
(gRNA) is a key question that we addressed here using Mason-Pfizer monkey virus (MPMV) …
Determinants of Genomic RNA Encapsidation in the Saccharomyces cerevisiae Long Terminal Repeat Retrotransposons Ty1 and Ty3
K Pachulska-Wieczorek, SFJ Le Grice, KJ Purzycka - Viruses, 2016 - mdpi.com
Long-terminal repeat (LTR) retrotransposons are transposable genetic elements that
replicate intracellularly, and can be considered progenitors of retroviruses. Ty1 and Ty3 are …
replicate intracellularly, and can be considered progenitors of retroviruses. Ty1 and Ty3 are …
Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition
Background The nucleocapsid (NC) domain of HIV-1 Gag is responsible for specific
recognition and packaging of genomic RNA (gRNA) into new viral particles. This occurs …
recognition and packaging of genomic RNA (gRNA) into new viral particles. This occurs …
Retroviral-like determinants and functions required for dimerization of Ty1 retrotransposon RNA
During replication of long terminal repeat (LTR)-retrotransposons, their proteins and
genome (g) RNA assemble into virus-like particles (VLPs) that are not infectious but …
genome (g) RNA assemble into virus-like particles (VLPs) that are not infectious but …
Human T-cell leukemia virus type 1 Gag domains have distinct RNA-binding specificities with implications for RNA packaging and dimerization
Human T-cell leukemia virus type 1 (HTLV-1) is the first retrovirus that has conclusively been
shown to cause human diseases. In HIV-1, specific interactions between the nucleocapsid …
shown to cause human diseases. In HIV-1, specific interactions between the nucleocapsid …
Exploring structural determinants and the role of nucleolin in formation of the long-range interactions between untranslated regions of p53 mRNA
p53 protein is a key regulator of cellular homeostasis by coordinating the framework of
antiproliferative pathways as a response to various stress factors. Although the main …
antiproliferative pathways as a response to various stress factors. Although the main …