Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice
H Zheng, P Xu, Q Jiang, Q Xu, Y Zheng, J Yan, H Ji… - Microbiome, 2021 - Springer
Background Modification of the gut microbiota has been reported to reduce the incidence of
type 1 diabetes mellitus (T1D). We hypothesized that the gut microbiota shifts might also …
type 1 diabetes mellitus (T1D). We hypothesized that the gut microbiota shifts might also …
Microvascular basis of cognitive impairment in type 1 diabetes
The complex computations of the brain require a constant supply of blood flow to meet its
immense metabolic needs. Perturbations in blood supply, even in the smallest vascular …
immense metabolic needs. Perturbations in blood supply, even in the smallest vascular …
Case report: Ketogenic diet alleviated anxiety and depression associated with insulin-dependent diabetes management
E Winje, I Lake, SN Dankel - Frontiers in Nutrition, 2024 - frontiersin.org
Differentiating between an irrational versus a rational fear of hypoglycemia has treatment
implications and presents significant challenge for clinicians facing patients with type 1 …
implications and presents significant challenge for clinicians facing patients with type 1 …
Alterations in functional connectivity of thalamus and primary somatosensory cortex in painful and painless diabetic peripheral neuropathy
OBJECTIVE In this study we aimed to investigate the functional connectivity of brain regions
involved in sensory processing in diabetes with and without painful and painless diabetic …
involved in sensory processing in diabetes with and without painful and painless diabetic …
[PDF][PDF] Network medicine-based epistasis detection in complex diseases: ready for quantum computing
Most heritable diseases are polygenic. To comprehend the underlying genetic architecture,
it is crucial to discover the clinically relevant epistatic interactions (EIs) between genomic …
it is crucial to discover the clinically relevant epistatic interactions (EIs) between genomic …
Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation
X Ye, Q Jiang, M Wu, Q Ye, H Zheng - Acta Pharmacologica Sinica, 2024 - nature.com
Fecal microbiota transplant (FMT) is becoming as a promising area of interest for treating
refractory diseases. In this study, we investigated the effects of FMT on diabetes-associated …
refractory diseases. In this study, we investigated the effects of FMT on diabetes-associated …
Different FreeSurfer versions might generate different statistical outcomes in case–control comparison studies
Purpose Neuroimaging pipelines have long been known to generate mildly differing results
depending on various factors, including software version. While considered generally …
depending on various factors, including software version. While considered generally …
Gray matter brain alterations in type 1 diabetes–findings based on detailed phenoty** of neuropathy status
SS Croosu, TM Hansen, J Røikjer… - Experimental and …, 2022 - thieme-connect.com
Aims This study investigated brain structure in patients of type 1 diabetes with diabetic
peripheral neuropathy (DPN) and type 1 diabetes with neuropathic pain and the …
peripheral neuropathy (DPN) and type 1 diabetes with neuropathic pain and the …
[HTML][HTML] Altered surface-based brain morphometry in type 1 diabetes and neuropathic pain
This study explored surface brain morphometry in type 1 diabetes including focus on painful
diabetic peripheral neuropathy (DPN). Brain MRI was obtained from 56 individuals with …
diabetic peripheral neuropathy (DPN). Brain MRI was obtained from 56 individuals with …
[HTML][HTML] Altered functional connectivity between brain structures in adults with type 1 diabetes and polyneuropathy
Objective Alterations of the central nervous system are increasingly being recognized as a
part of diabetes, especially in the thalamus and the default mode network (DMN). However …
part of diabetes, especially in the thalamus and the default mode network (DMN). However …