Myeloproliferative neoplasm (MPN)-associated myelofibrosis (MF) is characterized by
cytopenias, marrow fibrosis, constitutional symptoms, extramedullary hematopoiesis …

Adiponectin, one of the most ubiquitous adipokines found in the blood, plays a major role in
glucolipid metabolism and energy metabolism and regulation. In recent years, a growing …

In this phase 2 open-label randomized study, 31 patients with intermediate-2 or high-risk
myelofibrosis received fedratinib 300, 400 or 500 mg once daily in consecutive 4-week …

Pulmonary fibrosis is one of the most common complications of paraquat (PQ) poisoning,
which demands for more effective therapies. Accumulating evidence suggests adiponectin …

Neovascularization in retina and choroid involves interplay of many cytokines and growth
factors. Vascular endothelial growth factor (VEGF) being a pro-angiogenic molecule has …

Remodeling of the pulmonary arteries is a common feature among the heterogeneous
disorders that cause pulmonary hypertension. In these disorders, the remodeled pulmonary …

There is increasing evidence that inflammation plays a pivotal role in the pathogenesis of
some forms of pulmonary hypertension (PH). We recently demonstrated that deficiency of …

Background Cellulite, which appears as orange peel‐type or cottage cheese‐like dimpling
of the skin on the thighs and buttocks, is a complex, multifactorial, cosmetic disorder of the …

Background In addition to insulin‐sensitizing effects, adiponectin influences several
mechanisms involved in pulmonary arterial hypertension (PAH) pathobiology. Insulin …

Age-related macular degeneration (AMD) is a leading cause of central blindness in the
elderly population. The wet type of AMD is characterized by extensive growth of new …